WallStSmart

Arrowhead Pharmaceuticals Inc (ARWR)vsRegeneron Pharmaceuticals Inc (REGN)

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Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 1215% more annual revenue ($14.34B vs $1.09B). REGN leads profitability with a 31.4% profit margin vs 18.5%. REGN trades at a lower P/E of 17.9x. REGN earns a higher WallStSmart Score of 58/100 (C).

ARWR

Buy

58

out of 100

Grade: C

Growth: 8.7Profit: 8.5Value: 5.7Quality: 5.8
Piotroski: 4/9Altman Z: 0.27

REGN

Buy

58

out of 100

Grade: C

Growth: 4.0Profit: 7.5Value: 7.3Quality: 7.3
Piotroski: 3/9Altman Z: 4.68
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ARWRSignificantly Overvalued (-71.1%)

Margin of Safety

-71.1%

Fair Value

$35.97

Current Price

$60.77

$24.80 premium

UndervaluedFair: $35.97Overvalued
REGNSignificantly Overvalued (-165.8%)

Margin of Safety

-165.8%

Fair Value

$281.93

Current Price

$749.47

$467.54 premium

UndervaluedFair: $281.93Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ARWR2 strengths · Avg: 10.0/10
Return on EquityProfitability
75.5%10/10

Every $100 of equity generates 76 in profit

Revenue GrowthGrowth
104.6%10/10

Revenue surging 104.6% year-over-year

REGN6 strengths · Avg: 8.8/10
Profit MarginProfitability
31.4%10/10

Keeps 31 of every $100 in revenue as profit

Altman Z-ScoreHealth
4.6810/10

Safe zone — low bankruptcy risk

Market CapQuality
$78.41B9/10

Large-cap with strong market position

P/E RatioValuation
17.9x8/10

Attractively priced relative to earnings

Price/BookValuation
2.5x8/10

Reasonable price relative to book value

Operating MarginProfitability
23.1%8/10

Strong operational efficiency at 23.1%

Areas to Watch

ARWR3 concerns · Avg: 3.3/10
P/E RatioValuation
38.0x4/10

Premium valuation, high expectations priced in

Price/BookValuation
14.7x4/10

Trading at 14.7x book value

Altman Z-ScoreHealth
0.272/10

Distress zone — elevated risk

REGN4 concerns · Avg: 3.3/10
PEG RatioValuation
1.564/10

Expensive relative to growth rate

Revenue GrowthGrowth
2.5%4/10

2.5% revenue growth

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

EPS GrowthGrowth
-2.6%2/10

Earnings declined 2.6%

Comparative Analysis Report

WallStSmart Research

Bull Case : ARWR

The strongest argument for ARWR centers on Return on Equity, Revenue Growth. Profitability is solid with margins at 18.5% and operating margin at 15.5%. Revenue growth of 104.6% demonstrates continued momentum.

Bull Case : REGN

The strongest argument for REGN centers on Profit Margin, Altman Z-Score, Market Cap. Profitability is solid with margins at 31.4% and operating margin at 23.1%.

Bear Case : ARWR

The primary concerns for ARWR are P/E Ratio, Price/Book, Altman Z-Score.

Bear Case : REGN

The primary concerns for REGN are PEG Ratio, Revenue Growth, Piotroski F-Score.

Key Dynamics to Monitor

ARWR profiles as a growth stock while REGN is a value play — different risk/reward profiles.

ARWR carries more volatility with a beta of 1.30 — expect wider price swings.

ARWR is growing revenue faster at 104.6% — sustainability is the question.

REGN generates stronger free cash flow (922M), providing more financial flexibility.

Bottom Line

ARWR scores higher overall (58/100 vs 58/100), backed by strong 18.5% margins and 104.6% revenue growth. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Arrowhead Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Arrowhead Pharmaceuticals, Inc. develops drugs for the treatment of intractable diseases in the United States. The company is headquartered in Pasadena, California.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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