WallStSmart

AstraZeneca PLC (AZN)vsHarmony Biosciences Holdings (HRMY)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 6622% more annual revenue ($60.44B vs $899.11M). AZN leads profitability with a 17.2% profit margin vs 16.2%. HRMY trades at a lower P/E of 13.6x. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

HRMY

Buy

53

out of 100

Grade: C-

Growth: 6.7Profit: 8.0Value: 6.0Quality: 8.5
Piotroski: 3/9Altman Z: 3.37
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+10.7%)

Margin of Safety

+10.7%

Fair Value

$193.96

Current Price

$173.30

$20.66 discount

UndervaluedFair: $193.96Overvalued

Intrinsic value data unavailable for HRMY.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$261.94B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.7%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

HRMY5 strengths · Avg: 8.6/10
Altman Z-ScoreHealth
3.3710/10

Safe zone — low bankruptcy risk

Debt/EquityHealth
0.239/10

Conservative balance sheet, low leverage

P/E RatioValuation
13.6x8/10

Attractively priced relative to earnings

Price/BookValuation
2.3x8/10

Reasonable price relative to book value

Revenue GrowthGrowth
16.6%8/10

16.6% revenue growth

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
25.4x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

HRMY3 concerns · Avg: 2.7/10
Market CapQuality
$1.94B3/10

Smaller company, higher risk/reward

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

EPS GrowthGrowth
-29.5%2/10

Earnings declined 29.5%

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : HRMY

The strongest argument for HRMY centers on Altman Z-Score, Debt/Equity, P/E Ratio. Profitability is solid with margins at 16.2% and operating margin at 17.3%. Revenue growth of 16.6% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : HRMY

The primary concerns for HRMY are Market Cap, Piotroski F-Score, EPS Growth.

Key Dynamics to Monitor

AZN profiles as a mature stock while HRMY is a growth play — different risk/reward profiles.

HRMY carries more volatility with a beta of 0.94 — expect wider price swings.

HRMY is growing revenue faster at 16.6% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 53/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Harmony Biosciences Holdings

HEALTHCARE · BIOTECHNOLOGY · USA

Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, develops and markets therapies for patients with rare neurological disorders. The company is headquartered in Plymouth Meeting, Pennsylvania.

Visit Website →

Want to dig deeper into these stocks?