WallStSmart

AstraZeneca PLC (AZN)vsHeron Therapeuti (HRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 40617% more annual revenue ($61.37B vs $150.71M). AZN leads profitability with a 17.0% profit margin vs -20.5%. AZN earns a higher WallStSmart Score of 65/100 (B-).

AZN

Strong Buy

65

out of 100

Grade: B-

Growth: 5.3Profit: 8.0Value: 6.7Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

HRTX

Avoid

27

out of 100

Grade: F

Growth: 4.7Profit: 2.0Value: 5.0Quality: 4.5
Piotroski: 4/9Altman Z: -9.57
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+20.4%)

Margin of Safety

+20.4%

Fair Value

$196.68

Current Price

$156.45

$40.23 discount

UndervaluedFair: $196.68Overvalued

Intrinsic value data unavailable for HRTX.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$243.86B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.8%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
23.5%8/10

Strong operational efficiency at 23.5%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

HRTX0 strengths · Avg: 0/10

No standout strengths identified

Areas to Watch

AZN2 concerns · Avg: 3.0/10
EPS GrowthGrowth
2.5%4/10

2.5% earnings growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

HRTX4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$92.90M3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-338.6%2/10

ROE of -338.6% — below average capital efficiency

Revenue GrowthGrowth
-10.8%2/10

Revenue declined 10.8%

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.0% and operating margin at 23.5%. PEG of 1.40 suggests the stock is reasonably priced for its growth.

Bull Case : HRTX

HRTX has a balanced fundamental profile.

Bear Case : AZN

The primary concerns for AZN are EPS Growth, Altman Z-Score.

Bear Case : HRTX

The primary concerns for HRTX are EPS Growth, Market Cap, Return on Equity. Debt-to-equity of 21.48 is elevated, increasing financial risk.

Key Dynamics to Monitor

AZN profiles as a mature stock while HRTX is a turnaround play — different risk/reward profiles.

HRTX carries more volatility with a beta of 1.67 — expect wider price swings.

AZN is growing revenue faster at 6.4% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (65/100 vs 27/100), backed by strong 17.0% margins. Both earn "Strong Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Heron Therapeuti

HEALTHCARE · BIOTECHNOLOGY · USA

Heron Therapeutics, Inc., a biotechnology company, is dedicated to developing treatments to address unmet medical needs. The company is headquartered in San Diego, California.

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