WallStSmart

AstraZeneca PLC (AZN)vsOpus Genetics, Inc. (IRD)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 622526% more annual revenue ($61.37B vs $9.86M). AZN leads profitability with a 17.0% profit margin vs 0.0%. AZN earns a higher WallStSmart Score of 60/100 (C+).

AZN

Buy

60

out of 100

Grade: C+

Growth: 5.3Profit: 8.0Value: 6.7Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

IRD

Avoid

19

out of 100

Grade: F

Growth: 2.7Profit: 2.5Value: 6.0Quality: 6.5
Piotroski: 3/9Altman Z: -6.86
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+15.3%)

Margin of Safety

+15.3%

Fair Value

$196.36

Current Price

$166.27

$30.09 discount

UndervaluedFair: $196.36Overvalued
IRDUndervalued (+29.1%)

Margin of Safety

+29.1%

Fair Value

$4.64

Current Price

$3.85

$0.79 discount

UndervaluedFair: $4.64Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$263.12B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.8%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
23.5%8/10

Strong operational efficiency at 23.5%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

IRD1 strengths · Avg: 10.0/10
Debt/EquityHealth
-2.6910/10

Conservative balance sheet, low leverage

Areas to Watch

AZN2 concerns · Avg: 3.0/10
EPS GrowthGrowth
2.5%4/10

2.5% earnings growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

IRD4 concerns · Avg: 3.3/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$336.94M3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.0% and operating margin at 23.5%. PEG of 1.44 suggests the stock is reasonably priced for its growth.

Bull Case : IRD

The strongest argument for IRD centers on Debt/Equity.

Bear Case : AZN

The primary concerns for AZN are EPS Growth, Altman Z-Score.

Bear Case : IRD

The primary concerns for IRD are EPS Growth, Market Cap, Profit Margin.

Key Dynamics to Monitor

AZN profiles as a mature stock while IRD is a value play — different risk/reward profiles.

IRD carries more volatility with a beta of 0.58 — expect wider price swings.

AZN is growing revenue faster at 6.4% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (60/100 vs 19/100), backed by strong 17.0% margins. IRD offers better value entry with a 29.1% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Opus Genetics, Inc.

HEALTHCARE · BIOTECHNOLOGY · USA

Opus Genetics, Inc. (IRD) is a pioneering biotechnology company dedicated to advancing gene therapies for rare retinal diseases that affect vision. Utilizing cutting-edge gene-editing techniques and a strong research framework, Opus Genetics seeks to address significant unmet medical needs in ocular health. The company's innovative pipeline, bolstered by ongoing clinical trials and strategic partnerships, positions it favorably within the dynamic healthcare sector, offering substantial growth potential for institutional investors.

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