WallStSmart

AstraZeneca PLC (AZN)vsUniqure NV (QURE)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 333946% more annual revenue ($60.44B vs $18.09M). AZN leads profitability with a 17.2% profit margin vs 0.0%. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

QURE

Avoid

28

out of 100

Grade: F

Growth: 4.7Profit: 2.5Value: 5.0Quality: 6.5
Piotroski: 5/9Altman Z: -1.71
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued

Intrinsic value data unavailable for QURE.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

QURE1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
127.3%10/10

Revenue surging 127.3% year-over-year

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

QURE4 concerns · Avg: 3.0/10
Price/BookValuation
8.3x4/10

Trading at 8.3x book value

Market CapQuality
$1.74B3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Return on EquityProfitability
-228.2%2/10

ROE of -228.2% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : QURE

The strongest argument for QURE centers on Revenue Growth. Revenue growth of 127.3% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : QURE

The primary concerns for QURE are Price/Book, Market Cap, Profit Margin.

Key Dynamics to Monitor

AZN profiles as a mature stock while QURE is a hypergrowth play — different risk/reward profiles.

QURE carries more volatility with a beta of 1.00 — expect wider price swings.

QURE is growing revenue faster at 127.3% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 28/100), backed by strong 17.2% margins and 12.5% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Uniqure NV

HEALTHCARE · BIOTECHNOLOGY · USA

uniQure NV, a gene therapy company, is dedicated to developing treatments for patients suffering from genetic and other devastating diseases. The company is headquartered in Amsterdam, the Netherlands.

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