WallStSmart

Compugen (CGEN)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 16910% more annual revenue ($12.59B vs $74.00M). CGEN leads profitability with a 47.6% profit margin vs 35.0%. CGEN appears more attractively valued with a PEG of 1.29. VRTX earns a higher WallStSmart Score of 64/100 (C+).

CGEN

Buy

60

out of 100

Grade: C+

Growth: 8.0Profit: 8.0Value: 7.0Quality: 7.0
Piotroski: 5/9Altman Z: -0.74

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for CGEN.

VRTXUndervalued (+46.5%)

Margin of Safety

+46.5%

Fair Value

$963.47

Current Price

$515.44

$448.03 discount

UndervaluedFair: $963.47Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

CGEN6 strengths · Avg: 9.7/10
P/E RatioValuation
6.5x10/10

Attractively priced relative to earnings

Return on EquityProfitability
36.5%10/10

Every $100 of equity generates 37 in profit

Profit MarginProfitability
47.6%10/10

Keeps 48 of every $100 in revenue as profit

Revenue GrowthGrowth
107.0%10/10

Revenue surging 107.0% year-over-year

Debt/EquityHealth
0.0310/10

Conservative balance sheet, low leverage

Price/BookValuation
2.6x8/10

Reasonable price relative to book value

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Debt/EquityHealth
0.1010/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$130.56B9/10

Large-cap with strong market position

Return on EquityProfitability
21.8%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

CGEN4 concerns · Avg: 2.5/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$233.97M3/10

Smaller company, higher risk/reward

Altman Z-ScoreHealth
-0.742/10

Distress zone — elevated risk

Operating MarginProfitability
-339.6%1/10

Operating margin of -339.6%

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.894/10

Expensive relative to growth rate

P/E RatioValuation
30.0x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : CGEN

The strongest argument for CGEN centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 47.6% and operating margin at -339.6%. Revenue growth of 107.0% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : CGEN

The primary concerns for CGEN are EPS Growth, Market Cap, Altman Z-Score.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

CGEN profiles as a growth stock while VRTX is a mature play — different risk/reward profiles.

CGEN carries more volatility with a beta of 2.79 — expect wider price swings.

CGEN is growing revenue faster at 107.0% — sustainability is the question.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

VRTX scores higher overall (64/100 vs 60/100), backed by strong 35.0% margins and 12.5% revenue growth. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Compugen

HEALTHCARE · BIOTECHNOLOGY · USA

Compugen Ltd., a clinical-stage therapeutic discovery and development company, is engaged in the research, development, and commercialization of therapeutic candidates and products in Israel, the United States, and Europe. The company is headquartered in Holon, Israel.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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