WallStSmart

Curis Inc (CRIS)vsBeOne Medicines AG (ONC)

VS
⚡

Smart Verdict

WallStSmart Research — data-driven comparison

BeOne Medicines AG generates 153041% more annual revenue ($6.61B vs $4.31M). ONC leads profitability with a 13.9% profit margin vs 0.0%. CRIS trades at a lower P/E of 0.5x. ONC earns a higher WallStSmart Score of 70/100 (B-).

CRIS

Avoid

34

out of 100

Grade: F

Growth: 2.7Profit: 2.5Value: 8.3Quality: 5.0
Piotroski: 4/9Altman Z: -88.09

ONC

Strong Buy

70

out of 100

Grade: B-

Growth: 10.0Profit: 7.5Value: 6.7Quality: 7.0
Piotroski: 5/9Altman Z: 0.75
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

CRISUndervalued (+80.5%)

Margin of Safety

+80.5%

Fair Value

$5.44

Current Price

$0.57

$4.87 discount

UndervaluedFair: $5.44Overvalued
ONCUndervalued (+81.0%)

Margin of Safety

+81.0%

Fair Value

$1845.68

Current Price

$415.96

$1429.72 discount

UndervaluedFair: $1845.68Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

CRIS3 strengths · Avg: 9.7/10
P/E RatioValuation
0.5x10/10

Attractively priced relative to earnings

Price/BookValuation
0.2x10/10

Reasonable price relative to book value

Debt/EquityHealth
0.229/10

Conservative balance sheet, low leverage

ONC5 strengths · Avg: 9.0/10
Revenue GrowthGrowth
33.8%10/10

Revenue surging 33.8% year-over-year

EPS GrowthGrowth
212.5%10/10

Earnings expanding 212.5% YoY

Debt/EquityHealth
0.209/10

Conservative balance sheet, low leverage

PEG RatioValuation
0.828/10

Growing faster than its price suggests

Operating MarginProfitability
22.2%8/10

Strong operational efficiency at 22.2%

Areas to Watch

CRIS4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$1.46M3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Return on EquityProfitability
-166.6%2/10

ROE of -166.6% — below average capital efficiency

ONC3 concerns · Avg: 2.7/10
Price/BookValuation
8.2x4/10

Trading at 8.2x book value

P/E RatioValuation
52.2x2/10

Premium valuation, high expectations priced in

Altman Z-ScoreHealth
0.752/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : CRIS

The strongest argument for CRIS centers on P/E Ratio, Price/Book, Debt/Equity.

Bull Case : ONC

The strongest argument for ONC centers on Revenue Growth, EPS Growth, Debt/Equity. Revenue growth of 33.8% demonstrates continued momentum. PEG of 0.82 suggests the stock is reasonably priced for its growth.

Bear Case : CRIS

The primary concerns for CRIS are EPS Growth, Market Cap, Profit Margin.

Bear Case : ONC

The primary concerns for ONC are Price/Book, P/E Ratio, Altman Z-Score. A P/E of 52.2x leaves little room for execution misses.

Key Dynamics to Monitor

CRIS profiles as a value stock while ONC is a growth play — different risk/reward profiles.

CRIS carries more volatility with a beta of 3.10 — expect wider price swings.

ONC is growing revenue faster at 33.8% — sustainability is the question.

ONC generates stronger free cash flow (474M), providing more financial flexibility.

Bottom Line

ONC scores higher overall (70/100 vs 34/100) and 33.8% revenue growth. CRIS offers better value entry with a 80.5% margin of safety. Both earn "Strong Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Curis Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Curis, Inc., a biotechnology company, is dedicated to the discovery and development of drug candidates for the treatment of human cancers in the United States. The company is headquartered in Lexington, Massachusetts.

BeOne Medicines AG

HEALTHCARE · BIOTECHNOLOGY · USA

BeiGene, Ltd., an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company is headquartered in Camana Bay, the Cayman Islands.

Visit Website →

Want to dig deeper into these stocks?