WallStSmart

Fortress Biotech Inc (FBIO)vsVertex Pharmaceuticals Inc (VRTX)

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Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 18285% more annual revenue ($12.59B vs $68.47M). FBIO leads profitability with a 163.3% profit margin vs 35.0%. FBIO trades at a lower P/E of 0.9x. VRTX earns a higher WallStSmart Score of 64/100 (C+).

FBIO

Buy

57

out of 100

Grade: C

Growth: 4.0Profit: 4.0Value: 8.3Quality: 6.5
Piotroski: 4/9Altman Z: -4.86

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.0Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

FBIOUndervalued (+73.4%)

Margin of Safety

+73.4%

Fair Value

$13.79

Current Price

$2.28

$11.51 discount

UndervaluedFair: $13.79Overvalued
VRTXUndervalued (+45.6%)

Margin of Safety

+45.6%

Fair Value

$960.21

Current Price

$526.19

$434.02 discount

UndervaluedFair: $960.21Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

FBIO3 strengths · Avg: 10.0/10
P/E RatioValuation
0.9x10/10

Attractively priced relative to earnings

Price/BookValuation
0.5x10/10

Reasonable price relative to book value

Profit MarginProfitability
163.3%10/10

Keeps 163 of every $100 in revenue as profit

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Debt/EquityHealth
0.1010/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$130.87B9/10

Large-cap with strong market position

Return on EquityProfitability
21.8%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

FBIO4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$84.04M3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-108.7%2/10

ROE of -108.7% — below average capital efficiency

Free Cash FlowQuality
$-59.36M2/10

Negative free cash flow — burning cash

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.894/10

Expensive relative to growth rate

P/E RatioValuation
30.0x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : FBIO

The strongest argument for FBIO centers on P/E Ratio, Price/Book, Profit Margin. Profitability is solid with margins at 163.3% and operating margin at -53.5%. Revenue growth of 14.0% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : FBIO

The primary concerns for FBIO are EPS Growth, Market Cap, Return on Equity.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

FBIO carries more volatility with a beta of 1.19 — expect wider price swings.

FBIO is growing revenue faster at 14.0% — sustainability is the question.

VRTX generates stronger free cash flow (1.0B), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

VRTX scores higher overall (64/100 vs 57/100), backed by strong 35.0% margins and 12.5% revenue growth. FBIO offers better value entry with a 73.4% margin of safety. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Fortress Biotech Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Fortress Biotech, Inc., a biopharmaceutical company, develops and markets pharmaceutical and biotech products. The company is headquartered in New York, New York.

Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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