WallStSmart

Genmab AS (GMAB)vsVertex Pharmaceuticals Inc (VRTX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Vertex Pharmaceuticals Inc generates 205% more annual revenue ($12.59B vs $4.13B). VRTX leads profitability with a 35.0% profit margin vs 19.1%. VRTX appears more attractively valued with a PEG of 1.89. VRTX earns a higher WallStSmart Score of 64/100 (C+).

GMAB

Buy

53

out of 100

Grade: C-

Growth: 4.0Profit: 8.0Value: 6.0Quality: 6.0
Piotroski: 2/9Altman Z: 1.70

VRTX

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 9.0Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 3.61
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

GMABUndervalued (+48.6%)

Margin of Safety

+48.6%

Fair Value

$58.54

Current Price

$32.47

$26.07 discount

UndervaluedFair: $58.54Overvalued
VRTXUndervalued (+46.5%)

Margin of Safety

+46.5%

Fair Value

$963.47

Current Price

$519.51

$443.96 discount

UndervaluedFair: $963.47Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

GMAB2 strengths · Avg: 9.0/10
Operating MarginProfitability
35.2%10/10

Strong operational efficiency at 35.2%

Revenue GrowthGrowth
24.9%8/10

Revenue surging 24.9% year-over-year

VRTX6 strengths · Avg: 9.7/10
Profit MarginProfitability
35.0%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
38.1%10/10

Strong operational efficiency at 38.1%

Debt/EquityHealth
0.1010/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
3.6110/10

Safe zone — low bankruptcy risk

Market CapQuality
$130.56B9/10

Large-cap with strong market position

Return on EquityProfitability
21.8%9/10

Every $100 of equity generates 22 in profit

Areas to Watch

GMAB4 concerns · Avg: 3.3/10
P/E RatioValuation
26.7x4/10

Moderate valuation

Altman Z-ScoreHealth
1.704/10

Distress zone — elevated risk

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

PEG RatioValuation
5.762/10

Expensive relative to growth rate

VRTX3 concerns · Avg: 3.7/10
PEG RatioValuation
1.894/10

Expensive relative to growth rate

P/E RatioValuation
30.0x4/10

Moderate valuation

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : GMAB

The strongest argument for GMAB centers on Operating Margin, Revenue Growth. Profitability is solid with margins at 19.1% and operating margin at 35.2%. Revenue growth of 24.9% demonstrates continued momentum.

Bull Case : VRTX

The strongest argument for VRTX centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 35.0% and operating margin at 38.1%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : GMAB

The primary concerns for GMAB are P/E Ratio, Altman Z-Score, Piotroski F-Score.

Bear Case : VRTX

The primary concerns for VRTX are PEG Ratio, P/E Ratio, Piotroski F-Score.

Key Dynamics to Monitor

GMAB profiles as a growth stock while VRTX is a mature play — different risk/reward profiles.

GMAB carries more volatility with a beta of 0.70 — expect wider price swings.

GMAB is growing revenue faster at 24.9% — sustainability is the question.

VRTX generates stronger free cash flow (1.0B), providing more financial flexibility.

Bottom Line

VRTX scores higher overall (64/100 vs 53/100), backed by strong 35.0% margins and 12.5% revenue growth. GMAB offers better value entry with a 48.6% margin of safety. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Genmab AS

HEALTHCARE · BIOTECHNOLOGY · USA

Genmab A / S develops antibody therapies for the treatment of cancer and other diseases mainly in Denmark. The company is headquartered in Copenhagen, Denmark.

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Vertex Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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