WallStSmart

Insmed Inc (INSM)vsMadrigal Pharmaceuticals Inc (MDGL)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Madrigal Pharmaceuticals Inc generates 58% more annual revenue ($958.40M vs $606.42M). INSM leads profitability with a -2.1% profit margin vs -30.1%. INSM earns a higher WallStSmart Score of 39/100 (F).

INSM

Hold

39

out of 100

Grade: F

Growth: 6.0Profit: 2.0Value: 6.7Quality: 6.3
Piotroski: 6/9Altman Z: -3.77

MDGL

Avoid

31

out of 100

Grade: F

Growth: 4.3Profit: 2.0Value: 5.0Quality: 5.8
Piotroski: 4/9Altman Z: 0.22

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

INSM0 strengths · Avg: 0/10

No standout strengths identified

MDGL0 strengths · Avg: 0/10

No standout strengths identified

Areas to Watch

INSM4 concerns · Avg: 3.0/10
Revenue GrowthGrowth
1.5%4/10

1.5% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Price/BookValuation
43.0x2/10

Trading at 43.0x book value

Return on EquityProfitability
-2.5%2/10

ROE of -2.5% — below average capital efficiency

MDGL4 concerns · Avg: 3.5/10
Price/BookValuation
17.5x4/10

Trading at 17.5x book value

Revenue GrowthGrowth
2.1%4/10

2.1% revenue growth

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Return on EquityProfitability
-42.5%2/10

ROE of -42.5% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : INSM

PEG of 1.09 suggests the stock is reasonably priced for its growth.

Bull Case : MDGL

MDGL has a balanced fundamental profile.

Bear Case : INSM

The primary concerns for INSM are Revenue Growth, EPS Growth, Price/Book.

Bear Case : MDGL

The primary concerns for MDGL are Price/Book, Revenue Growth, EPS Growth.

Key Dynamics to Monitor

INSM carries more volatility with a beta of 1.17 — expect wider price swings.

MDGL is growing revenue faster at 2.1% — sustainability is the question.

MDGL generates stronger free cash flow (-134M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

INSM scores higher overall (39/100 vs 31/100). Both earn "Hold" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Insmed Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Insmed Incorporated, a biopharmaceutical company, develops and markets therapies for patients with rare and serious diseases. The company is headquartered in Bridgewater, New Jersey.

Madrigal Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic and liver diseases. The company is headquartered in West Conshohocken, Pennsylvania.

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