WallStSmart

Krystal Biotech Inc (KRYS)vsRegeneron Pharmaceuticals Inc (REGN)

VS
⚡

Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 3736% more annual revenue ($16.90B vs $440.48M). KRYS leads profitability with a 54.8% profit margin vs 28.5%. REGN trades at a lower P/E of 20.5x. REGN earns a higher WallStSmart Score of 78/100 (B+).

KRYS

Buy

65

out of 100

Grade: C+

Growth: 7.7Profit: 9.0Value: 4.7Quality: 9.0
Piotroski: 4/9Altman Z: 8.02

REGN

Strong Buy

78

out of 100

Grade: B+

Growth: 8.7Profit: 8.0Value: 6.7Quality: 8.5
Piotroski: 2/9Altman Z: 4.44
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for KRYS.

REGNUndervalued (+39.8%)

Margin of Safety

+39.8%

Fair Value

$1500.88

Current Price

$904.35

$596.53 discount

UndervaluedFair: $1500.88Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

KRYS6 strengths · Avg: 9.3/10
Profit MarginProfitability
54.8%10/10

Keeps 55 of every $100 in revenue as profit

Operating MarginProfitability
49.0%10/10

Strong operational efficiency at 49.0%

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
8.0210/10

Safe zone — low bankruptcy risk

Revenue GrowthGrowth
24.1%8/10

Revenue surging 24.1% year-over-year

EPS GrowthGrowth
38.8%8/10

Earnings expanding 38.8% YoY

REGN6 strengths · Avg: 9.7/10
Operating MarginProfitability
40.5%10/10

Strong operational efficiency at 40.5%

Revenue GrowthGrowth
36.3%10/10

Revenue surging 36.3% year-over-year

Debt/EquityHealth
0.0810/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.4410/10

Safe zone — low bankruptcy risk

Market CapQuality
$95.99B9/10

Large-cap with strong market position

Profit MarginProfitability
28.5%9/10

Keeps 29 of every $100 in revenue as profit

Areas to Watch

KRYS1 concerns · Avg: 2.0/10
P/E RatioValuation
40.3x2/10

Premium valuation, high expectations priced in

REGN2 concerns · Avg: 3.5/10
PEG RatioValuation
1.584/10

Expensive relative to growth rate

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : KRYS

The strongest argument for KRYS centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 54.8% and operating margin at 49.0%. Revenue growth of 24.1% demonstrates continued momentum.

Bull Case : REGN

The strongest argument for REGN centers on Operating Margin, Revenue Growth, Debt/Equity. Profitability is solid with margins at 28.5% and operating margin at 40.5%. Revenue growth of 36.3% demonstrates continued momentum.

Bear Case : KRYS

The primary concerns for KRYS are P/E Ratio. A P/E of 40.3x leaves little room for execution misses.

Bear Case : REGN

The primary concerns for REGN are PEG Ratio, Piotroski F-Score.

Key Dynamics to Monitor

KRYS carries more volatility with a beta of 0.50 — expect wider price swings.

REGN is growing revenue faster at 36.3% — sustainability is the question.

REGN generates stronger free cash flow (1.5B), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

REGN scores higher overall (78/100 vs 65/100), backed by strong 28.5% margins and 36.3% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Krystal Biotech Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Krystal Biotech, Inc., a clinical-stage biotechnology company, is dedicated to the field of redosable gene therapy to treat serious rare diseases in the United States. The company is headquartered in Pittsburgh, Pennsylvania.

Visit Website →

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

Want to dig deeper into these stocks?