WallStSmart

Krystal Biotech Inc (KRYS)vsRegeneron Pharmaceuticals Inc (REGN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 3586% more annual revenue ($14.34B vs $389.13M). KRYS leads profitability with a 52.6% profit margin vs 31.4%. REGN trades at a lower P/E of 17.9x. REGN earns a higher WallStSmart Score of 58/100 (C).

KRYS

Buy

57

out of 100

Grade: C

Growth: 6.3Profit: 9.0Value: 5.7Quality: 9.0
Piotroski: 4/9Altman Z: 7.95

REGN

Buy

58

out of 100

Grade: C

Growth: 4.0Profit: 7.5Value: 7.3Quality: 7.3
Piotroski: 3/9Altman Z: 4.68
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

KRYSSignificantly Overvalued (-57.2%)

Margin of Safety

-57.2%

Fair Value

$173.46

Current Price

$254.95

$81.49 premium

UndervaluedFair: $173.46Overvalued
REGNSignificantly Overvalued (-165.8%)

Margin of Safety

-165.8%

Fair Value

$281.93

Current Price

$749.47

$467.54 premium

UndervaluedFair: $281.93Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

KRYS5 strengths · Avg: 9.6/10
Profit MarginProfitability
52.6%10/10

Keeps 53 of every $100 in revenue as profit

Operating MarginProfitability
41.3%10/10

Strong operational efficiency at 41.3%

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
7.9510/10

Safe zone — low bankruptcy risk

Revenue GrowthGrowth
17.5%8/10

17.5% revenue growth

REGN6 strengths · Avg: 8.8/10
Profit MarginProfitability
31.4%10/10

Keeps 31 of every $100 in revenue as profit

Altman Z-ScoreHealth
4.6810/10

Safe zone — low bankruptcy risk

Market CapQuality
$78.41B9/10

Large-cap with strong market position

P/E RatioValuation
17.9x8/10

Attractively priced relative to earnings

Price/BookValuation
2.5x8/10

Reasonable price relative to book value

Operating MarginProfitability
23.1%8/10

Strong operational efficiency at 23.1%

Areas to Watch

KRYS1 concerns · Avg: 4.0/10
P/E RatioValuation
36.1x4/10

Premium valuation, high expectations priced in

REGN4 concerns · Avg: 3.3/10
PEG RatioValuation
1.564/10

Expensive relative to growth rate

Revenue GrowthGrowth
2.5%4/10

2.5% revenue growth

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

EPS GrowthGrowth
-2.6%2/10

Earnings declined 2.6%

Comparative Analysis Report

WallStSmart Research

Bull Case : KRYS

The strongest argument for KRYS centers on Profit Margin, Operating Margin, Debt/Equity. Profitability is solid with margins at 52.6% and operating margin at 41.3%. Revenue growth of 17.5% demonstrates continued momentum.

Bull Case : REGN

The strongest argument for REGN centers on Profit Margin, Altman Z-Score, Market Cap. Profitability is solid with margins at 31.4% and operating margin at 23.1%.

Bear Case : KRYS

The primary concerns for KRYS are P/E Ratio.

Bear Case : REGN

The primary concerns for REGN are PEG Ratio, Revenue Growth, Piotroski F-Score.

Key Dynamics to Monitor

KRYS profiles as a growth stock while REGN is a value play — different risk/reward profiles.

KRYS carries more volatility with a beta of 0.51 — expect wider price swings.

KRYS is growing revenue faster at 17.5% — sustainability is the question.

REGN generates stronger free cash flow (922M), providing more financial flexibility.

Bottom Line

REGN scores higher overall (58/100 vs 57/100), backed by strong 31.4% margins. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Krystal Biotech Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Krystal Biotech, Inc., a clinical-stage biotechnology company, is dedicated to the field of redosable gene therapy to treat serious rare diseases in the United States. The company is headquartered in Pittsburgh, Pennsylvania.

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Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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