WallStSmart

Merck & Company Inc (MRK)vsProtagonist Therapeutics Inc (PTGX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Merck & Company Inc generates 141179% more annual revenue ($65.01B vs $46.02M). MRK leads profitability with a 28.1% profit margin vs -282.8%. MRK earns a higher WallStSmart Score of 59/100 (C).

MRK

Buy

59

out of 100

Grade: C

Growth: 4.0Profit: 9.5Value: 4.7Quality: 4.8
Piotroski: 3/9

PTGX

Avoid

28

out of 100

Grade: F

Growth: 7.3Profit: 2.0Value: 5.0Quality: 5.0
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

MRKOvervalued (-13.2%)

Margin of Safety

-13.2%

Fair Value

$96.48

Current Price

$109.18

$12.70 premium

UndervaluedFair: $96.48Overvalued

Intrinsic value data unavailable for PTGX.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

MRK6 strengths · Avg: 9.2/10
Market CapQuality
$274.03B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
36.9%10/10

Every $100 of equity generates 37 in profit

Operating MarginProfitability
32.8%10/10

Strong operational efficiency at 32.8%

Profit MarginProfitability
28.1%9/10

Keeps 28 of every $100 in revenue as profit

P/E RatioValuation
15.2x8/10

Attractively priced relative to earnings

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

PTGX1 strengths · Avg: 10.0/10
EPS GrowthGrowth
351.3%10/10

Earnings expanding 351.3% YoY

Areas to Watch

MRK3 concerns · Avg: 2.3/10
Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

PEG RatioValuation
3.362/10

Expensive relative to growth rate

EPS GrowthGrowth
-19.3%2/10

Earnings declined 19.3%

PTGX4 concerns · Avg: 2.5/10
Price/BookValuation
10.1x4/10

Trading at 10.1x book value

Return on EquityProfitability
-20.2%2/10

ROE of -20.2% — below average capital efficiency

Revenue GrowthGrowth
-95.6%2/10

Revenue declined 95.6%

Free Cash FlowQuality
$-38.42M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : MRK

The strongest argument for MRK centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 28.1% and operating margin at 32.8%.

Bull Case : PTGX

The strongest argument for PTGX centers on EPS Growth.

Bear Case : MRK

The primary concerns for MRK are Piotroski F-Score, PEG Ratio, EPS Growth.

Bear Case : PTGX

The primary concerns for PTGX are Price/Book, Return on Equity, Revenue Growth.

Key Dynamics to Monitor

MRK profiles as a value stock while PTGX is a turnaround play — different risk/reward profiles.

PTGX carries more volatility with a beta of 2.11 — expect wider price swings.

MRK is growing revenue faster at 5.0% — sustainability is the question.

MRK generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

MRK scores higher overall (59/100 vs 28/100), backed by strong 28.1% margins. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Merck & Company Inc

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

Merck & Co. is an American multinational pharmaceutical company headquartered in Kenilworth, New Jersey. It is named after the Merck family, which set up Merck Group in Germany in 1668.

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Protagonist Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Protagonist Therapeutics, Inc., a clinical-stage biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address unmet medical needs. The company is headquartered in Newark, California.

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