WallStSmart

Crinetics Pharmaceuticals Inc (CRNX) Stock Analysis — PE Ratio, PS Ratio, Intrinsic Value & 2030 Price Target

Crinetics Pharmaceuticals Inc stock (CRNX) is currently trading at $36.34. Crinetics Pharmaceuticals Inc PS ratio (Price-to-Sales) is 467.61. Analyst consensus price target for CRNX is $83.50. WallStSmart rates CRNX as Sell.

  • CRNX PE ratio analysis and historical PE chart
  • CRNX PS ratio (Price-to-Sales) history and trend
  • CRNX intrinsic value — DCF, Graham Number, EPV models
  • CRNX stock price prediction 2025 2026 2027 2028 2029 2030
  • CRNX fair value vs current price
  • CRNX insider transactions and insider buying
  • Is CRNX undervalued or overvalued?
  • Crinetics Pharmaceuticals Inc financial analysis — revenue, earnings, cash flow
  • CRNX Piotroski F-Score and Altman Z-Score
  • CRNX analyst price target and Smart Rating
CRNX

Crinetics Pharmaceuticals Inc

NASDAQHEALTHCARE
$36.34
$1.97 (5.73%)
52W$24.10
$57.99
Target$83.50+129.8%

📊 No data available

Try selecting a different time range

WallStSmart

Smart Analysis

Crinetics Pharmaceuticals Inc (CRNX) · 7 metrics scored

Smart Score

30
out of 100
Grade: F
Avoid
Investment Rating

Category Performance

WallStSmart pulls financial metrics like revenue growth, profit margins, and valuation ratios and scores each one from 0 to 10 based on how strong or weak it is. Those 10 scores are grouped into 4 categories: Growth, Profitability, Valuation, and Quality — which form the 4 axes of the spider chart you see. The categories are then combined into a final score out of 100, but not equally. Growth and Profitability together count for 60% of the total, because a fast-growing profitable business matters more than just a cheap one. That final number maps to a rating (Strong Buy, Buy, Hold, Avoid) and a letter grade, giving you one clear Stock Rating.

Investment Thesis

Strong fundamentals in revenue growth, institutional own.. Concerns around return on equity and operating margin. Significant fundamental concerns warrant caution or avoidance.

Crinetics Pharmaceuticals Inc (CRNX) Key Strengths (3)

Avg Score: 9.0/10
Revenue GrowthGrowth
158.40%10/10

Revenue surging 158.40% year-over-year

Institutional Own.Quality
110.11%10/10

110.11% of shares held by major funds and institutions

Market CapQuality
$3.60B7/10

Mid-cap company balancing growth potential with stability

Supporting Valuation Data

CRNX Target Price
$83.5
86% Upside

Crinetics Pharmaceuticals Inc (CRNX) Areas to Watch (4)

Avg Score: 1.5/10
Return on EquityProfitability
-40.20%0/10

Company is destroying shareholder value

Operating MarginProfitability
-2170.00%0/10

Losing money on operations

Price/SalesValuation
467.612/10

Very expensive at 467.6x annual revenue

Price/BookValuation
3.664/10

Premium pricing at 3.7x book value

Supporting Valuation Data

Price/Sales (TTM)
467.61
Overvalued
EV/Revenue
344.98
Overvalued

Crinetics Pharmaceuticals Inc (CRNX) Detailed Analysis Report

Overall Assessment

This company scores 30/100 in our Smart Analysis, earning a F grade. Out of 7 metrics analyzed, 3 register as strengths (avg 9.0/10) while 4 fall into concern territory (avg 1.5/10). The category breakdown reveals uneven performance, with some areas requiring attention.

The Bull Case

The strongest argument centers on Revenue Growth, Institutional Own., Market Cap. Growth metrics are encouraging with Revenue Growth at 158.40%.

The Bear Case

The primary concerns are Return on Equity, Operating Margin, Price/Sales. Some valuation metrics including Price/Sales (467.61), Price/Book (3.66) suggest expensive pricing. Profitability pressure is visible in Return on Equity at -40.20%, Operating Margin at -2170.00%.

Key Dynamics to Monitor

Three factors to monitor going forward. First, whether Return on Equity improves, as this is the primary drag on the overall score. Second, margin trajectory, with Return on Equity at -40.20% needing improvement to support the investment thesis. Third, growth sustainability, with Revenue Growth at 158.40% strong but requiring continuation.

Risk Considerations

Based on the metric profile, this is a higher risk investment. There are more areas of concern than strength, warranting a more conservative position size. Investors should size positions according to their risk tolerance and maintain diversification.

Bottom Line

Fundamental challenges outweigh strengths at current levels. Return on Equity and Operating Margin are the primary drags. Consider waiting for meaningful improvement before committing capital.

Disclaimer: Smart Analysis is a scoring system developed by WallStSmart Team. Scores update daily using multi-model valuation framework. Always conduct your own research and consult with financial advisors before making investment decisions.

CRNX Price-to-Sales(PS) Ratio Chart

Historical valuation based on market cap ÷ trailing 12-month revenue

CRNX's Price-to-Sales ratio of 467.61x trades at a deep discount to its historical average of 1574.79x (8th percentile). The current valuation is 91% below its historical high of 4927.29x set in Jan 2026, and 35% above its historical low of 347.55x in Mar 2023. Over the past 12 months, the PS ratio has compressed from ~3426.6x as trailing revenue scaled faster than the stock price.

Compare CRNX with Competitors

Top BIOTECHNOLOGY stocks by market cap

Compare any two stocks →

WallStSmart Analysis Synopsis

Data-driven financial summary for Crinetics Pharmaceuticals Inc (CRNX) · HEALTHCAREBIOTECHNOLOGY

The Big Picture

Crinetics Pharmaceuticals Inc is in a high-growth phase, prioritizing rapid expansion over margins. Revenue reached 8M with 158% growth year-over-year. The company is currently unprofitable, posting a 0.0% profit margin.

Key Findings

Strong Revenue Growth

Revenue growing at 158% YoY, reaching 8M. This pace significantly outperforms most BIOTECHNOLOGY peers.

Heavy R&D Investment

Spending 1105% of revenue (85M) on R&D, reinforcing its commitment to innovation and future growth.

Negative Free Cash Flow

Free cash flow is -93M, meaning the company is burning cash. This may be acceptable for high-growth companies investing heavily.

What to Watch Next

Growth sustainability: can Crinetics Pharmaceuticals Inc maintain 158%+ revenue growth, or will competition slow it down?

Sector dynamics: monitor BIOTECHNOLOGY industry trends, competitive moves, and regulatory changes that could impact Crinetics Pharmaceuticals Inc.

Bottom Line

Crinetics Pharmaceuticals Inc is a high-conviction growth story with revenue accelerating at 158% while profitability is still developing. For growth-oriented investors, the trajectory is compelling. For value investors, the thin 0.0% margins and premium valuation suggest patience until the unit economics mature further.

This synopsis is generated from publicly available financial data. It is not financial advice. Always conduct your own research and consult a qualified financial advisor before making investment decisions.

Insider Transactions(17 last 3 months)

Total Buys
11
Total Sells
6

Data sourced from SEC Form 4 filings

Last updated: 8:27:47 AM

About Crinetics Pharmaceuticals Inc(CRNX)

Exchange

NASDAQ

Sector

HEALTHCARE

Industry

BIOTECHNOLOGY

Country

USA

Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of therapies for rare endocrine diseases and endocrine-related tumors. The company is headquartered in San Diego, California.