WallStSmart

Iovance Biotherapeutics Inc (IOVA) Stock Analysis — PE Ratio, PS Ratio, Intrinsic Value & 2030 Price Target

Iovance Biotherapeutics Inc stock (IOVA) is currently trading at $3.75. Iovance Biotherapeutics Inc PS ratio (Price-to-Sales) is 5.77. Analyst consensus price target for IOVA is $9.00. WallStSmart rates IOVA as Sell.

  • IOVA PE ratio analysis and historical PE chart
  • IOVA PS ratio (Price-to-Sales) history and trend
  • IOVA intrinsic value — DCF, Graham Number, EPV models
  • IOVA stock price prediction 2025 2026 2027 2028 2029 2030
  • IOVA fair value vs current price
  • IOVA insider transactions and insider buying
  • Is IOVA undervalued or overvalued?
  • Iovance Biotherapeutics Inc financial analysis — revenue, earnings, cash flow
  • IOVA Piotroski F-Score and Altman Z-Score
  • IOVA analyst price target and Smart Rating
IOVA

Iovance Biotherapeutics Inc

NASDAQHEALTHCARE
$3.75
$0.13 (3.59%)
52W$1.64
$5.63
Target$9.00+140.0%

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WallStSmart

Smart Analysis

Iovance Biotherapeutics Inc (IOVA) · 8 metrics scored

Smart Score

30
out of 100
Grade: F
Avoid
Investment Rating

Category Performance

WallStSmart pulls financial metrics like revenue growth, profit margins, and valuation ratios and scores each one from 0 to 10 based on how strong or weak it is. Those 10 scores are grouped into 4 categories: Growth, Profitability, Valuation, and Quality — which form the 4 axes of the spider chart you see. The categories are then combined into a final score out of 100, but not equally. Growth and Profitability together count for 60% of the total, because a fast-growing profitable business matters more than just a cheap one. That final number maps to a rating (Strong Buy, Buy, Hold, Avoid) and a letter grade, giving you one clear Stock Rating.

Investment Thesis

Strong fundamentals in institutional own.. Concerns around return on equity and operating margin. Significant fundamental concerns warrant caution or avoidance.

Iovance Biotherapeutics Inc (IOVA) Key Strengths (1)

Avg Score: 10.0/10
Institutional Own.Quality
71.09%10/10

71.09% of shares held by major funds and institutions

Supporting Valuation Data

IOVA Target Price
$9
182% Upside

Iovance Biotherapeutics Inc (IOVA) Areas to Watch (7)

Avg Score: 3.0/10
Return on EquityProfitability
-55.50%0/10

Company is destroying shareholder value

Operating MarginProfitability
-84.70%0/10

Losing money on operations

Profit MarginProfitability
-148.40%0/10

Company is losing money with a negative profit margin

Price/SalesValuation
5.774/10

Premium valuation at 5.8x annual revenue

Market CapQuality
$1.52B5/10

Small-cap company with higher risk but more growth potential

Price/BookValuation
2.186/10

Fairly priced relative to book value

Revenue GrowthGrowth
17.70%6/10

Solid revenue growth at 17.70% per year

Supporting Valuation Data

Price/Sales (TTM)
5.77
Premium

Iovance Biotherapeutics Inc (IOVA) Detailed Analysis Report

Overall Assessment

This company scores 30/100 in our Smart Analysis, earning a F grade. Out of 8 metrics analyzed, 1 register as strengths (avg 10.0/10) while 7 fall into concern territory (avg 3.0/10). The category breakdown reveals uneven performance, with some areas requiring attention.

The Bull Case

The strongest argument centers on Institutional Own..

The Bear Case

The primary concerns are Return on Equity, Operating Margin, Profit Margin. Some valuation metrics including Price/Sales (5.77), Price/Book (2.18) suggest expensive pricing. Growth concerns include Revenue Growth at 17.70%, which may limit upside. Profitability pressure is visible in Return on Equity at -55.50%, Operating Margin at -84.70%, Profit Margin at -148.40%.

Key Dynamics to Monitor

Three factors to monitor going forward. First, whether Return on Equity improves, as this is the primary drag on the overall score. Second, margin trajectory, with Return on Equity at -55.50% needing improvement to support the investment thesis. Third, growth sustainability, with Revenue Growth at 17.70% needing to reaccelerate.

Risk Considerations

Based on the metric profile, this is a higher risk investment. There are more areas of concern than strength, warranting a more conservative position size. Investors should size positions according to their risk tolerance and maintain diversification.

Bottom Line

Fundamental challenges outweigh strengths at current levels. Return on Equity and Operating Margin are the primary drags. Consider waiting for meaningful improvement before committing capital.

Disclaimer: Smart Analysis is a scoring system developed by WallStSmart Team. Scores update daily using multi-model valuation framework. Always conduct your own research and consult with financial advisors before making investment decisions.

IOVA Price-to-Sales(PS) Ratio Chart

Historical valuation based on market cap ÷ trailing 12-month revenue

IOVA's Price-to-Sales ratio of 5.77x trades at a deep discount to its historical average of 2006.25x (19th percentile). The current valuation is 100% below its historical high of 9657.33x set in Nov 2023, and 50% above its historical low of 3.84x in Jan 2026. Over the past 12 months, the PS ratio has compressed from ~8.6x as trailing revenue scaled faster than the stock price.

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WallStSmart Analysis Synopsis

Data-driven financial summary for Iovance Biotherapeutics Inc (IOVA) · HEALTHCAREBIOTECHNOLOGY

The Big Picture

Iovance Biotherapeutics Inc is a strong growth company balancing expansion with improving profitability. Revenue reached 264M with 18% growth year-over-year. The company is currently unprofitable, posting a -148.4% profit margin.

Key Findings

Heavy R&D Investment

Spending 26% of revenue (69M) on R&D, reinforcing its commitment to innovation and future growth.

Operating at a Loss

The company is unprofitable with a -148.4% profit margin. The path to breakeven will be the key catalyst.

Negative Free Cash Flow

Free cash flow is -62M, meaning the company is burning cash. This may be acceptable for high-growth companies investing heavily.

What to Watch Next

Sector dynamics: monitor BIOTECHNOLOGY industry trends, competitive moves, and regulatory changes that could impact Iovance Biotherapeutics Inc.

Bottom Line

Iovance Biotherapeutics Inc offers an attractive blend of growth (18% revenue expansion) and improving fundamentals. The company is transitioning from pure growth to profitable growth, a critical inflection point. Watch for sustained margin expansion as the key signal.

This synopsis is generated from publicly available financial data. It is not financial advice. Always conduct your own research and consult a qualified financial advisor before making investment decisions.

Insider Transactions(39 last 3 months)

Total Buys
16
Total Sells
23

Data sourced from SEC Form 4 filings

Last updated: 2:28:45 PM

About Iovance Biotherapeutics Inc(IOVA)

Exchange

NASDAQ

Sector

HEALTHCARE

Industry

BIOTECHNOLOGY

Country

USA

Iovance Biotherapeutics, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing cancer immunotherapy products to harness the power of a patient's immune system to eradicate cancer cells. The company is headquartered in San Carlos, California.