WallStSmart

MeiraGTx Holdings PLC (MGTX) Stock Analysis — PE Ratio, PS Ratio, Intrinsic Value & 2030 Price Target

MeiraGTx Holdings PLC stock (MGTX) is currently trading at $7.41. MeiraGTx Holdings PLC PS ratio (Price-to-Sales) is 22.46. Analyst consensus price target for MGTX is $26.75. WallStSmart rates MGTX as Sell.

  • MGTX PE ratio analysis and historical PE chart
  • MGTX PS ratio (Price-to-Sales) history and trend
  • MGTX intrinsic value — DCF, Graham Number, EPV models
  • MGTX stock price prediction 2025 2026 2027 2028 2029 2030
  • MGTX fair value vs current price
  • MGTX insider transactions and insider buying
  • Is MGTX undervalued or overvalued?
  • MeiraGTx Holdings PLC financial analysis — revenue, earnings, cash flow
  • MGTX Piotroski F-Score and Altman Z-Score
  • MGTX analyst price target and Smart Rating
MGTX

MeiraGTx Holdings

NASDAQHEALTHCARE
$7.41
$0.24 (-3.14%)
52W$4.55
$9.73
Target$26.75+261.0%

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WallStSmart

Smart Analysis

MeiraGTx Holdings PLC (MGTX) · 7 metrics scored

Smart Score

15
out of 100
Grade: F
Avoid
Investment Rating

Category Performance

WallStSmart pulls financial metrics like revenue growth, profit margins, and valuation ratios and scores each one from 0 to 10 based on how strong or weak it is. Those 10 scores are grouped into 4 categories: Growth, Profitability, Valuation, and Quality — which form the 4 axes of the spider chart you see. The categories are then combined into a final score out of 100, but not equally. Growth and Profitability together count for 60% of the total, because a fast-growing profitable business matters more than just a cheap one. That final number maps to a rating (Strong Buy, Buy, Hold, Avoid) and a letter grade, giving you one clear Stock Rating.

Investment Thesis

Strong fundamentals in institutional own.. Concerns around return on equity and operating margin. Significant fundamental concerns warrant caution or avoidance.

MeiraGTx Holdings PLC (MGTX) Key Strengths (1)

Avg Score: 8.0/10
Institutional Own.Quality
66.34%8/10

66.34% held by institutions, strong professional interest

Supporting Valuation Data

Forward P/E
1.615
Attractive
MGTX Target Price
$26.75
254% Upside

MeiraGTx Holdings PLC (MGTX) Areas to Watch (6)

Avg Score: 1.5/10
Return on EquityProfitability
-611.00%0/10

Company is destroying shareholder value

Operating MarginProfitability
-11232.00%0/10

Losing money on operations

Revenue GrowthGrowth
-96.20%0/10

Revenue declining -96.20%, a shrinking business

Price/SalesValuation
22.462/10

Very expensive at 22.5x annual revenue

Price/BookValuation
225.312/10

Very expensive at 225.3x book value

Market CapQuality
$616M5/10

Small-cap company with higher risk but more growth potential

Supporting Valuation Data

Price/Sales (TTM)
22.46
Overvalued
EV/Revenue
23.81
Overvalued

MeiraGTx Holdings PLC (MGTX) Detailed Analysis Report

Overall Assessment

This company scores 15/100 in our Smart Analysis, earning a F grade. Out of 7 metrics analyzed, 1 register as strengths (avg 8.0/10) while 6 fall into concern territory (avg 1.5/10). The category breakdown reveals uneven performance, with some areas requiring attention.

The Bull Case

The strongest argument centers on Institutional Own..

The Bear Case

The primary concerns are Return on Equity, Operating Margin, Revenue Growth. Some valuation metrics including Price/Sales (22.46), Price/Book (225.31) suggest expensive pricing. Growth concerns include Revenue Growth at -96.20%, which may limit upside. Profitability pressure is visible in Return on Equity at -611.00%, Operating Margin at -11232.00%.

Key Dynamics to Monitor

Three factors to monitor going forward. First, whether Return on Equity improves, as this is the primary drag on the overall score. Second, margin trajectory, with Return on Equity at -611.00% needing improvement to support the investment thesis. Third, growth sustainability, with Revenue Growth at -96.20% needing to reaccelerate.

Risk Considerations

Based on the metric profile, this is a higher risk investment. There are more areas of concern than strength, warranting a more conservative position size. Investors should size positions according to their risk tolerance and maintain diversification.

Bottom Line

Fundamental challenges outweigh strengths at current levels. Return on Equity and Operating Margin are the primary drags. Consider waiting for meaningful improvement before committing capital.

Disclaimer: Smart Analysis is a scoring system developed by WallStSmart Team. Scores update daily using multi-model valuation framework. Always conduct your own research and consult with financial advisors before making investment decisions.

MGTX Price-to-Sales(PS) Ratio Chart

Historical valuation based on market cap ÷ trailing 12-month revenue

MGTX's Price-to-Sales ratio of 22.46x trades 45% below its historical average of 40.85x (36th percentile). The current valuation is 80% below its historical high of 111.2x set in Oct 2021, and 81% above its historical low of 12.38x in May 2025. Over the past 12 months, the PS ratio has expanded from ~17.7x, reflecting growing market expectations outpacing revenue growth.

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WallStSmart Analysis Synopsis

Data-driven financial summary for MeiraGTx Holdings PLC (MGTX) · HEALTHCAREBIOTECHNOLOGY

The Big Picture

MeiraGTx Holdings PLC operates as a stable business with moderate growth and solid fundamentals. Revenue reached 27M with 96% decline year-over-year.

Key Findings

Heavy R&D Investment

Spending 119% of revenue (33M) on R&D, reinforcing its commitment to innovation and future growth.

Revenue Decline

Revenue contracted 96% YoY. Worth determining whether this is cyclical or structural.

Negative Free Cash Flow

Free cash flow is -13M, meaning the company is burning cash. This may be acceptable for high-growth companies investing heavily.

What to Watch Next

Sector dynamics: monitor BIOTECHNOLOGY industry trends, competitive moves, and regulatory changes that could impact MeiraGTx Holdings PLC.

Bottom Line

MeiraGTx Holdings PLC offers stability with moderate growth and solid fundamentals. The valuation may present an opportunity for patient investors, though limited growth means returns will likely come from dividends and modest capital appreciation rather than explosive gains.

This synopsis is generated from publicly available financial data. It is not financial advice. Always conduct your own research and consult a qualified financial advisor before making investment decisions.

Insider Transactions(46 last 3 months)

Total Buys
15
Total Sells
31
Dec 31, 2025(1 transaction)
PERCEPTIVE, ADVISORS LLC
Director, 10% Owner
Sell
Shares
-2,300,000

Data sourced from SEC Form 4 filings

Last updated: 11:50:06 AM

About MeiraGTx Holdings PLC(MGTX)

Exchange

NASDAQ

Sector

HEALTHCARE

Industry

BIOTECHNOLOGY

Country

USA

MeiraGTx Holdings plc, a clinical-stage gene therapy company, focused on developing treatments for patients living with serious illnesses. The company is headquartered in New York, New York.