WallStSmart

Tango Therapeutics Inc (TNGX) Stock Analysis — PE Ratio, PS Ratio, Intrinsic Value & 2030 Price Target

Tango Therapeutics Inc stock (TNGX) is currently trading at $20.88. Tango Therapeutics Inc PS ratio (Price-to-Sales) is 44.42. Analyst consensus price target for TNGX is $19.67. WallStSmart rates TNGX as Sell.

  • TNGX PE ratio analysis and historical PE chart
  • TNGX PS ratio (Price-to-Sales) history and trend
  • TNGX intrinsic value — DCF, Graham Number, EPV models
  • TNGX stock price prediction 2025 2026 2027 2028 2029 2030
  • TNGX fair value vs current price
  • TNGX insider transactions and insider buying
  • Is TNGX undervalued or overvalued?
  • Tango Therapeutics Inc financial analysis — revenue, earnings, cash flow
  • TNGX Piotroski F-Score and Altman Z-Score
  • TNGX analyst price target and Smart Rating
TNGX

Tango Therapeutics Inc

NASDAQHEALTHCARE
$20.88
$1.40 (7.19%)
52W$1.03
$19.80
Target$19.67-5.8%

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WallStSmart

Smart Analysis

Tango Therapeutics Inc (TNGX) · 8 metrics scored

Smart Score

18
out of 100
Grade: F
Avoid
Investment Rating

Category Performance

WallStSmart pulls financial metrics like revenue growth, profit margins, and valuation ratios and scores each one from 0 to 10 based on how strong or weak it is. Those 10 scores are grouped into 4 categories: Growth, Profitability, Valuation, and Quality — which form the 4 axes of the spider chart you see. The categories are then combined into a final score out of 100, but not equally. Growth and Profitability together count for 60% of the total, because a fast-growing profitable business matters more than just a cheap one. That final number maps to a rating (Strong Buy, Buy, Hold, Avoid) and a letter grade, giving you one clear Stock Rating.

Investment Thesis

Strong fundamentals in institutional own.. Concerns around return on equity and operating margin. Significant fundamental concerns warrant caution or avoidance.

Tango Therapeutics Inc (TNGX) Key Strengths (2)

Avg Score: 8.5/10
Institutional Own.Quality
121.34%10/10

121.34% of shares held by major funds and institutions

Market CapQuality
$2.77B7/10

Mid-cap company balancing growth potential with stability

Supporting Valuation Data

TNGX Target Price
$19.67
47% Upside

Tango Therapeutics Inc (TNGX) Areas to Watch (6)

Avg Score: 0.7/10
Return on EquityProfitability
-37.20%0/10

Company is destroying shareholder value

Operating MarginProfitability
-178.40%0/10

Losing money on operations

Revenue GrowthGrowth
-100.00%0/10

Revenue declining -100.00%, a shrinking business

Profit MarginProfitability
-162.90%0/10

Company is losing money with a negative profit margin

Price/SalesValuation
44.422/10

Very expensive at 44.4x annual revenue

Price/BookValuation
8.002/10

Very expensive at 8.0x book value

Supporting Valuation Data

Price/Sales (TTM)
44.42
Overvalued
EV/Revenue
39.43
Overvalued

Tango Therapeutics Inc (TNGX) Detailed Analysis Report

Overall Assessment

This company scores 18/100 in our Smart Analysis, earning a F grade. Out of 8 metrics analyzed, 2 register as strengths (avg 8.5/10) while 6 fall into concern territory (avg 0.7/10). The category breakdown reveals uneven performance, with some areas requiring attention.

The Bull Case

The strongest argument centers on Institutional Own., Market Cap.

The Bear Case

The primary concerns are Return on Equity, Operating Margin, Revenue Growth. Some valuation metrics including Price/Sales (44.42), Price/Book (8.00) suggest expensive pricing. Growth concerns include Revenue Growth at -100.00%, which may limit upside. Profitability pressure is visible in Return on Equity at -37.20%, Operating Margin at -178.40%, Profit Margin at -162.90%.

Key Dynamics to Monitor

Three factors to monitor going forward. First, whether Return on Equity improves, as this is the primary drag on the overall score. Second, margin trajectory, with Return on Equity at -37.20% needing improvement to support the investment thesis. Third, growth sustainability, with Revenue Growth at -100.00% needing to reaccelerate.

Risk Considerations

Based on the metric profile, this is a higher risk investment. There are more areas of concern than strength, warranting a more conservative position size. Investors should size positions according to their risk tolerance and maintain diversification.

Bottom Line

Fundamental challenges outweigh strengths at current levels. Return on Equity and Operating Margin are the primary drags. Consider waiting for meaningful improvement before committing capital.

Disclaimer: Smart Analysis is a scoring system developed by WallStSmart Team. Scores update daily using multi-model valuation framework. Always conduct your own research and consult with financial advisors before making investment decisions.

TNGX Price-to-Sales(PS) Ratio Chart

Historical valuation based on market cap ÷ trailing 12-month revenue

TNGX's Price-to-Sales ratio of 44.42x trades 23% below its historical average of 57.89x (75th percentile). The current valuation is 81% below its historical high of 238.53x set in Sep 2021, and 851% above its historical low of 4.67x in Apr 2025. Over the past 12 months, the PS ratio has expanded from ~4.7x, reflecting growing market expectations outpacing revenue growth.

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WallStSmart Analysis Synopsis

Data-driven financial summary for Tango Therapeutics Inc (TNGX) · HEALTHCAREBIOTECHNOLOGY

The Big Picture

Tango Therapeutics Inc is in a turnaround phase, with management focused on restoring profitability. Revenue reached 62M with 100% decline year-over-year. The company is currently unprofitable, posting a -162.9% profit margin.

Key Findings

Heavy R&D Investment

Spending 53% of revenue (33M) on R&D, reinforcing its commitment to innovation and future growth.

Revenue Decline

Revenue contracted 100% YoY. Worth determining whether this is cyclical or structural.

Operating at a Loss

The company is unprofitable with a -162.9% profit margin. The path to breakeven will be the key catalyst.

What to Watch Next

Volatility is elevated with a beta of 1.81, so expect amplified moves relative to the broader market.

Sector dynamics: monitor BIOTECHNOLOGY industry trends, competitive moves, and regulatory changes that could impact Tango Therapeutics Inc.

Bottom Line

Tango Therapeutics Inc is in turnaround mode. The path to profitability remains the critical question. Speculative investors may see opportunity in the recovery story, but conservative investors should wait for consistent positive earnings before committing capital.

This synopsis is generated from publicly available financial data. It is not financial advice. Always conduct your own research and consult a qualified financial advisor before making investment decisions.

Insider Transactions

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About Tango Therapeutics Inc(TNGX)

Exchange

NASDAQ

Sector

HEALTHCARE

Industry

BIOTECHNOLOGY

Country

USA

Tango Therapeutics Inc. is a clinical-stage biotechnology company pioneering the development of targeted therapies aimed at addressing significant unmet needs in cancer treatment, particularly through the innovative concept of synthetic lethality. With a diverse pipeline of promising drug candidates, Tango is well-positioned to lead advancements in precision oncology, focusing on collaborative partnerships with leading research institutions to enhance its scientific capabilities. The company's strategic vision is to transform cancer care and improve patient outcomes, positioning it as a key player in the evolution of treatment paradigms in oncology.