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Vyne Therapeutics Inc (VYNE) Stock Analysis — PE Ratio, PS Ratio, Intrinsic Value & 2030 Price Target

Vyne Therapeutics Inc stock (VYNE) is currently trading at $0.60. Vyne Therapeutics Inc PS ratio (Price-to-Sales) is 35.35. Analyst consensus price target for VYNE is $2.00. WallStSmart rates VYNE as Sell.

  • VYNE PE ratio analysis and historical PE chart
  • VYNE PS ratio (Price-to-Sales) history and trend
  • VYNE intrinsic value — DCF, Graham Number, EPV models
  • VYNE stock price prediction 2025 2026 2027 2028 2029 2030
  • VYNE fair value vs current price
  • VYNE insider transactions and insider buying
  • Is VYNE undervalued or overvalued?
  • Vyne Therapeutics Inc financial analysis — revenue, earnings, cash flow
  • VYNE Piotroski F-Score and Altman Z-Score
  • VYNE analyst price target and Smart Rating
VYNE

Vyne Therapeutics Inc

NASDAQHEALTHCARE
$0.60
$0.01 (-1.61%)
52W$0.28
$1.99
Target$2.00+230.8%

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WallStSmart

Smart Analysis

Vyne Therapeutics Inc (VYNE) · 7 metrics scored

Smart Score

30
out of 100
Grade: F
Avoid
Investment Rating

Category Performance

WallStSmart pulls financial metrics like revenue growth, profit margins, and valuation ratios and scores each one from 0 to 10 based on how strong or weak it is. Those 10 scores are grouped into 4 categories: Growth, Profitability, Valuation, and Quality — which form the 4 axes of the spider chart you see. The categories are then combined into a final score out of 100, but not equally. Growth and Profitability together count for 60% of the total, because a fast-growing profitable business matters more than just a cheap one. That final number maps to a rating (Strong Buy, Buy, Hold, Avoid) and a letter grade, giving you one clear Stock Rating.

Investment Thesis

Strong fundamentals in price/book, revenue growth. Concerns around market cap and return on equity. Significant fundamental concerns warrant caution or avoidance.

Vyne Therapeutics Inc (VYNE) Key Strengths (2)

Avg Score: 10.0/10
Price/BookValuation
0.7310/10

Trading below book value, meaning the market prices it less than net assets

Revenue GrowthGrowth
54.80%10/10

Revenue surging 54.80% year-over-year

Supporting Valuation Data

VYNE Target Price
$2
244% Upside

Vyne Therapeutics Inc (VYNE) Areas to Watch (5)

Avg Score: 1.8/10
Return on EquityProfitability
-67.00%0/10

Company is destroying shareholder value

Operating MarginProfitability
-4015.00%0/10

Losing money on operations

Price/SalesValuation
35.352/10

Very expensive at 35.4x annual revenue

Market CapQuality
$20M3/10

Micro-cap company with very limited liquidity and high volatility

Institutional Own.Quality
26.79%4/10

Low institutional interest, mostly retail-driven

Supporting Valuation Data

Price/Sales (TTM)
35.35
Overvalued
EV/Revenue
10.04
Premium

Vyne Therapeutics Inc (VYNE) Detailed Analysis Report

Overall Assessment

This company scores 30/100 in our Smart Analysis, earning a F grade. Out of 7 metrics analyzed, 2 register as strengths (avg 10.0/10) while 5 fall into concern territory (avg 1.8/10). The category breakdown reveals uneven performance, with some areas requiring attention.

The Bull Case

The strongest argument centers on Price/Book, Revenue Growth. Valuation metrics including Price/Book (0.73) suggest the stock is attractively priced. Growth metrics are encouraging with Revenue Growth at 54.80%.

The Bear Case

The primary concerns are Return on Equity, Operating Margin, Price/Sales. Some valuation metrics including Price/Sales (35.35) suggest expensive pricing. Profitability pressure is visible in Return on Equity at -67.00%, Operating Margin at -4015.00%.

Key Dynamics to Monitor

Three factors to monitor going forward. First, whether Return on Equity improves, as this is the primary drag on the overall score. Second, margin trajectory, with Return on Equity at -67.00% needing improvement to support the investment thesis. Third, growth sustainability, with Revenue Growth at 54.80% strong but requiring continuation.

Risk Considerations

Based on the metric profile, this is a higher risk investment. There are more areas of concern than strength, warranting a more conservative position size. Investors should size positions according to their risk tolerance and maintain diversification.

Bottom Line

Fundamental challenges outweigh strengths at current levels. Return on Equity and Operating Margin are the primary drags. Consider waiting for meaningful improvement before committing capital.

Disclaimer: Smart Analysis is a scoring system developed by WallStSmart Team. Scores update daily using multi-model valuation framework. Always conduct your own research and consult with financial advisors before making investment decisions.

VYNE Price-to-Sales(PS) Ratio Chart

Historical valuation based on market cap ÷ trailing 12-month revenue

VYNE's Price-to-Sales ratio of 35.35x trades at a deep discount to its historical average of 81.74x (50th percentile). The current valuation is 92% below its historical high of 460.57x set in May 2023, and 2069% above its historical low of 1.63x in Nov 2021. Over the past 12 months, the PS ratio has compressed from ~112.9x as trailing revenue scaled faster than the stock price.

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WallStSmart Analysis Synopsis

Data-driven financial summary for Vyne Therapeutics Inc (VYNE) · HEALTHCAREBIOTECHNOLOGY

The Big Picture

Vyne Therapeutics Inc is in a high-growth phase, prioritizing rapid expansion over margins. Revenue reached 570,000 with 55% growth year-over-year.

Key Findings

Strong Revenue Growth

Revenue growing at 55% YoY, reaching 570,000. This pace significantly outperforms most BIOTECHNOLOGY peers.

Heavy R&D Investment

Spending 522% of revenue (3M) on R&D, reinforcing its commitment to innovation and future growth.

Negative Free Cash Flow

Free cash flow is -4M, meaning the company is burning cash. This may be acceptable for high-growth companies investing heavily.

What to Watch Next

Growth sustainability: can Vyne Therapeutics Inc maintain 55%+ revenue growth, or will competition slow it down?

Volatility is elevated with a beta of 2.03, so expect amplified moves relative to the broader market.

Sector dynamics: monitor BIOTECHNOLOGY industry trends, competitive moves, and regulatory changes that could impact Vyne Therapeutics Inc.

Bottom Line

Vyne Therapeutics Inc is a high-conviction growth story with revenue accelerating at 55% while profitability is still developing. For growth-oriented investors, the trajectory is compelling. For value investors, the thin 0.0% margins and premium valuation suggest patience until the unit economics mature further.

This synopsis is generated from publicly available financial data. It is not financial advice. Always conduct your own research and consult a qualified financial advisor before making investment decisions.

Insider Transactions

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About Vyne Therapeutics Inc(VYNE)

Exchange

NASDAQ

Sector

HEALTHCARE

Industry

BIOTECHNOLOGY

Country

USA

VYNE Therapeutics Inc., a pharmaceutical company, focuses on developing and commercializing various therapies for dermatology. The company is headquartered in Bridgewater, New Jersey.

Visit Vyne Therapeutics Inc (VYNE) Website
685 ROUTE 202/206 N, BRIDGEWATER, NJ, UNITED STATES, 08807