WallStSmart

Abeona Therapeutics Inc (ABEO)vsAstraZeneca PLC (AZN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 1009161% more annual revenue ($58.74B vs $5.82M). ABEO leads profitability with a 1223.0% profit margin vs 17.4%. ABEO trades at a lower P/E of 5.3x. AZN earns a higher WallStSmart Score of 64/100 (C+).

ABEO

Hold

46

out of 100

Grade: D+

Growth: 5.3Profit: 6.0Value: 8.3Quality: 5.0

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 8.0Value: 5.3Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ABEOUndervalued (+81.8%)

Margin of Safety

+81.8%

Fair Value

$27.73

Current Price

$5.34

$22.39 discount

UndervaluedFair: $27.73Overvalued
AZNUndervalued (+4.1%)

Margin of Safety

+4.1%

Fair Value

$214.51

Current Price

$187.37

$27.14 discount

UndervaluedFair: $214.51Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ABEO4 strengths · Avg: 9.5/10
P/E RatioValuation
5.3x10/10

Attractively priced relative to earnings

Return on EquityProfitability
70.1%10/10

Every $100 of equity generates 70 in profit

Profit MarginProfitability
1223.0%10/10

Keeps 1223 of every $100 in revenue as profit

Price/BookValuation
1.8x8/10

Reasonable price relative to book value

AZN5 strengths · Avg: 9.0/10
Market CapQuality
$287.11B10/10

Mega-cap, among the largest globally

EPS GrowthGrowth
53.9%10/10

Earnings expanding 53.9% YoY

Return on EquityProfitability
22.8%9/10

Every $100 of equity generates 23 in profit

Operating MarginProfitability
21.6%8/10

Strong operational efficiency at 21.6%

Free Cash FlowQuality
$1.38B8/10

Generating 1.4B in free cash flow

Areas to Watch

ABEO4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$303.75M3/10

Smaller company, higher risk/reward

Revenue GrowthGrowth
-100.0%2/10

Revenue declined 100.0%

Free Cash FlowQuality
$-19.11M2/10

Negative free cash flow — burning cash

AZN4 concerns · Avg: 3.5/10
PEG RatioValuation
1.544/10

Expensive relative to growth rate

P/E RatioValuation
27.9x4/10

Moderate valuation

Revenue GrowthGrowth
4.1%4/10

4.1% revenue growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ABEO

The strongest argument for ABEO centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 1223.0% and operating margin at -422.7%.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, EPS Growth, Return on Equity. Profitability is solid with margins at 17.4% and operating margin at 21.6%.

Bear Case : ABEO

The primary concerns for ABEO are EPS Growth, Market Cap, Revenue Growth.

Bear Case : AZN

The primary concerns for AZN are PEG Ratio, P/E Ratio, Revenue Growth.

Key Dynamics to Monitor

ABEO profiles as a declining stock while AZN is a value play — different risk/reward profiles.

ABEO carries more volatility with a beta of 1.21 — expect wider price swings.

AZN is growing revenue faster at 4.1% — sustainability is the question.

AZN generates stronger free cash flow (1.4B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 46/100), backed by strong 17.4% margins. ABEO offers better value entry with a 81.8% margin of safety. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Abeona Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Abeona Therapeutics Inc., a clinical-stage biopharmaceutical company, develops gene and cell therapies for rare, life-threatening genetic diseases. The company is headquartered in New York, New York.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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