WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsAstraZeneca PLC (AZN)

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Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 1310% more annual revenue ($60.44B vs $4.29B). AZN leads profitability with a 17.2% profit margin vs 12.6%. ALNY appears more attractively valued with a PEG of 0.50. ALNY earns a higher WallStSmart Score of 65/100 (B-).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 7.3Quality: 5.0

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.6%)

Margin of Safety

+86.6%

Fair Value

$2401.68

Current Price

$297.45

$2104.23 discount

UndervaluedFair: $2401.68Overvalued
AZNUndervalued (+4.8%)

Margin of Safety

+4.8%

Fair Value

$194.77

Current Price

$187.03

$7.74 discount

UndervaluedFair: $194.77Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.5/10
PEG RatioValuation
0.5010/10

Growing faster than its price suggests

Return on EquityProfitability
90.4%10/10

Every $100 of equity generates 90 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$286.37B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
23.5%9/10

Every $100 of equity generates 24 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
74.1x2/10

Premium valuation, high expectations priced in

Price/BookValuation
36.9x2/10

Trading at 36.9x book value

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.8x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on PEG Ratio, Return on Equity, Revenue Growth. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.50 suggests the stock is reasonably priced for its growth.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 74.1x leaves little room for execution misses.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Key Dynamics to Monitor

ALNY profiles as a growth stock while AZN is a mature play — different risk/reward profiles.

ALNY carries more volatility with a beta of 0.30 — expect wider price swings.

ALNY is growing revenue faster at 96.4% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

ALNY scores higher overall (65/100 vs 64/100) and 96.4% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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