WallStSmart

Arbutus Biopharma Corp (ABUS)vsAstraZeneca PLC (AZN)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 416992% more annual revenue ($58.74B vs $14.08M). AZN leads profitability with a 17.4% profit margin vs -237.9%. AZN earns a higher WallStSmart Score of 64/100 (C+).

ABUS

Avoid

17

out of 100

Grade: F

Growth: 2.7Profit: 2.0Value: 6.0Quality: 5.0

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.7Profit: 8.0Value: 5.3Quality: 5.0
Piotroski: 6/9Altman Z: 1.48
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ABUSUndervalued (+18.9%)

Margin of Safety

+18.9%

Fair Value

$5.13

Current Price

$4.13

$1.00 discount

UndervaluedFair: $5.13Overvalued
AZNUndervalued (+4.1%)

Margin of Safety

+4.1%

Fair Value

$214.51

Current Price

$187.37

$27.14 discount

UndervaluedFair: $214.51Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ABUS0 strengths · Avg: 0/10

No standout strengths identified

AZN5 strengths · Avg: 9.0/10
Market CapQuality
$287.11B10/10

Mega-cap, among the largest globally

EPS GrowthGrowth
53.9%10/10

Earnings expanding 53.9% YoY

Return on EquityProfitability
22.8%9/10

Every $100 of equity generates 23 in profit

Operating MarginProfitability
21.6%8/10

Strong operational efficiency at 21.6%

Free Cash FlowQuality
$1.38B8/10

Generating 1.4B in free cash flow

Areas to Watch

ABUS4 concerns · Avg: 3.3/10
Price/BookValuation
10.3x4/10

Trading at 10.3x book value

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$813.36M3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-38.5%2/10

ROE of -38.5% — below average capital efficiency

AZN4 concerns · Avg: 3.5/10
PEG RatioValuation
1.544/10

Expensive relative to growth rate

P/E RatioValuation
27.9x4/10

Moderate valuation

Revenue GrowthGrowth
4.1%4/10

4.1% revenue growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ABUS

ABUS has a balanced fundamental profile.

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, EPS Growth, Return on Equity. Profitability is solid with margins at 17.4% and operating margin at 21.6%.

Bear Case : ABUS

The primary concerns for ABUS are Price/Book, EPS Growth, Market Cap.

Bear Case : AZN

The primary concerns for AZN are PEG Ratio, P/E Ratio, Revenue Growth.

Key Dynamics to Monitor

ABUS profiles as a turnaround stock while AZN is a value play — different risk/reward profiles.

ABUS carries more volatility with a beta of 0.74 — expect wider price swings.

AZN is growing revenue faster at 4.1% — sustainability is the question.

AZN generates stronger free cash flow (1.4B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 17/100), backed by strong 17.4% margins. ABUS offers better value entry with a 18.9% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Arbutus Biopharma Corp

HEALTHCARE · BIOTECHNOLOGY · USA

Arbutus Biopharma Corporation, a biopharmaceutical company, is dedicated to the discovery, development, and commercialization of a cure for patients with chronic hepatitis B virus (HBV) infection in the United States. The company is headquartered in Warminster, Pennsylvania.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

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