WallStSmart

argenx NV ADR (ARGX)vsHarmony Biosciences Holdings (HRMY)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

argenx NV ADR generates 454% more annual revenue ($5.32B vs $959.90M). ARGX leads profitability with a 32.3% profit margin vs 18.9%. HRMY trades at a lower P/E of 13.5x. HRMY earns a higher WallStSmart Score of 75/100 (B).

ARGX

Strong Buy

73

out of 100

Grade: B

Growth: 10.0Profit: 9.5Value: 6.7Quality: 8.5
Piotroski: 3/9Altman Z: 4.92

HRMY

Strong Buy

75

out of 100

Grade: B

Growth: 10.0Profit: 8.5Value: 6.0Quality: 8.5
Piotroski: 3/9Altman Z: 3.37
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ARGXUndervalued (+64.8%)

Margin of Safety

+64.8%

Fair Value

$2371.09

Current Price

$984.39

$1386.70 discount

UndervaluedFair: $2371.09Overvalued

Intrinsic value data unavailable for HRMY.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ARGX6 strengths · Avg: 10.0/10
Return on EquityProfitability
30.8%10/10

Every $100 of equity generates 31 in profit

Profit MarginProfitability
32.3%10/10

Keeps 32 of every $100 in revenue as profit

Operating MarginProfitability
32.0%10/10

Strong operational efficiency at 32.0%

Revenue GrowthGrowth
59.3%10/10

Revenue surging 59.3% year-over-year

EPS GrowthGrowth
95.2%10/10

Earnings expanding 95.2% YoY

Debt/EquityHealth
0.0110/10

Conservative balance sheet, low leverage

HRMY6 strengths · Avg: 9.5/10
Operating MarginProfitability
34.2%10/10

Strong operational efficiency at 34.2%

Revenue GrowthGrowth
30.3%10/10

Revenue surging 30.3% year-over-year

EPS GrowthGrowth
88.2%10/10

Earnings expanding 88.2% YoY

Altman Z-ScoreHealth
3.3710/10

Safe zone — low bankruptcy risk

Debt/EquityHealth
0.159/10

Conservative balance sheet, low leverage

P/E RatioValuation
13.5x8/10

Attractively priced relative to earnings

Areas to Watch

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
39.4x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
183.0x2/10

Trading at 183.0x book value

HRMY1 concerns · Avg: 3.0/10
Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : ARGX

The strongest argument for ARGX centers on Return on Equity, Profit Margin, Operating Margin. Profitability is solid with margins at 32.3% and operating margin at 32.0%. Revenue growth of 59.3% demonstrates continued momentum.

Bull Case : HRMY

The strongest argument for HRMY centers on Operating Margin, Revenue Growth, EPS Growth. Profitability is solid with margins at 18.9% and operating margin at 34.2%. Revenue growth of 30.3% demonstrates continued momentum.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, Price/Book.

Bear Case : HRMY

The primary concerns for HRMY are Piotroski F-Score.

Key Dynamics to Monitor

HRMY carries more volatility with a beta of 0.93 — expect wider price swings.

ARGX is growing revenue faster at 59.3% — sustainability is the question.

ARGX generates stronger free cash flow (749M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

HRMY scores higher overall (75/100 vs 73/100), backed by strong 18.9% margins and 30.3% revenue growth. ARGX offers better value entry with a 64.8% margin of safety. Both earn "Strong Buy" and "Strong Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

Harmony Biosciences Holdings

HEALTHCARE · BIOTECHNOLOGY · USA

Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, develops and markets therapies for patients with rare neurological disorders. The company is headquartered in Plymouth Meeting, Pennsylvania.

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