WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsargenx NV ADR (ARGX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

argenx NV ADR generates 14% more annual revenue ($4.25B vs $3.71B). ARGX leads profitability with a 30.4% profit margin vs 8.4%. ARGX trades at a lower P/E of 36.0x. ARGX earns a higher WallStSmart Score of 63/100 (C+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

ARGX

Buy

63

out of 100

Grade: C+

Growth: 7.3Profit: 9.0Value: 7.3Quality: 6.0
Piotroski: 3/9
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1934.6%)

Margin of Safety

-1934.6%

Fair Value

$15.84

Current Price

$312.17

$296.33 premium

UndervaluedFair: $15.84Overvalued
ARGXSignificantly Overvalued (-527.8%)

Margin of Safety

-527.8%

Fair Value

$132.94

Current Price

$663.93

$530.99 premium

UndervaluedFair: $132.94Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

ARGX5 strengths · Avg: 9.0/10
Profit MarginProfitability
30.4%10/10

Keeps 30 of every $100 in revenue as profit

Revenue GrowthGrowth
74.6%10/10

Revenue surging 74.6% year-over-year

Return on EquityProfitability
20.2%9/10

Every $100 of equity generates 20 in profit

PEG RatioValuation
0.878/10

Growing faster than its price suggests

Operating MarginProfitability
28.1%8/10

Strong operational efficiency at 28.1%

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
136.9x2/10

Premium valuation, high expectations priced in

Price/BookValuation
52.4x2/10

Trading at 52.4x book value

ARGX3 concerns · Avg: 3.0/10
P/E RatioValuation
36.0x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

EPS GrowthGrowth
-32.0%2/10

Earnings declined 32.0%

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : ARGX

The strongest argument for ARGX centers on Profit Margin, Revenue Growth, Return on Equity. Profitability is solid with margins at 30.4% and operating margin at 28.1%. Revenue growth of 74.6% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 136.9x leaves little room for execution misses.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, EPS Growth.

Key Dynamics to Monitor

ALNY profiles as a hypergrowth stock while ARGX is a growth play — different risk/reward profiles.

ALNY carries more volatility with a beta of 0.38 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ARGX generates stronger free cash flow (407M), providing more financial flexibility.

Bottom Line

ARGX scores higher overall (63/100 vs 49/100), backed by strong 30.4% margins and 74.6% revenue growth. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

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