WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsargenx NV ADR (ARGX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 1% more annual revenue ($4.29B vs $4.24B). ARGX leads profitability with a 30.5% profit margin vs 12.6%. ALNY appears more attractively valued with a PEG of 0.59. ALNY earns a higher WallStSmart Score of 65/100 (B-).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 6.7Quality: 5.0

ARGX

Buy

61

out of 100

Grade: C+

Growth: 7.3Profit: 9.0Value: 6.7Quality: 6.0
Piotroski: 3/9
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.7%)

Margin of Safety

+86.7%

Fair Value

$2429.90

Current Price

$296.11

$2133.79 discount

UndervaluedFair: $2429.90Overvalued
ARGXUndervalued (+60.4%)

Margin of Safety

+60.4%

Fair Value

$2106.55

Current Price

$783.50

$1323.05 discount

UndervaluedFair: $2106.55Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.0/10
Return on EquityProfitability
90.4%10/10

Every $100 of equity generates 90 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

PEG RatioValuation
0.598/10

Growing faster than its price suggests

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

ARGX4 strengths · Avg: 9.3/10
Profit MarginProfitability
30.5%10/10

Keeps 31 of every $100 in revenue as profit

Revenue GrowthGrowth
73.0%10/10

Revenue surging 73.0% year-over-year

Return on EquityProfitability
20.2%9/10

Every $100 of equity generates 20 in profit

Operating MarginProfitability
27.4%8/10

Strong operational efficiency at 27.4%

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
74.6x2/10

Premium valuation, high expectations priced in

Price/BookValuation
49.7x2/10

Trading at 49.7x book value

ARGX4 concerns · Avg: 2.8/10
P/E RatioValuation
40.0x4/10

Premium valuation, high expectations priced in

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Price/BookValuation
165.6x2/10

Trading at 165.6x book value

EPS GrowthGrowth
-31.9%2/10

Earnings declined 31.9%

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth, PEG Ratio. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.59 suggests the stock is reasonably priced for its growth.

Bull Case : ARGX

The strongest argument for ARGX centers on Profit Margin, Revenue Growth, Return on Equity. Profitability is solid with margins at 30.5% and operating margin at 27.4%. Revenue growth of 73.0% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 74.6x leaves little room for execution misses.

Bear Case : ARGX

The primary concerns for ARGX are P/E Ratio, Piotroski F-Score, Price/Book.

Key Dynamics to Monitor

ALNY carries more volatility with a beta of 0.30 — expect wider price swings.

ALNY is growing revenue faster at 96.4% — sustainability is the question.

ARGX generates stronger free cash flow (407M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (65/100 vs 61/100) and 96.4% revenue growth. ARGX offers better value entry with a 60.4% margin of safety. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

argenx NV ADR

HEALTHCARE · BIOTECHNOLOGY · USA

argenx SE, a clinical-phase biotechnology company, focuses on the development of antibody-based therapies for the treatment of autoimmune diseases, hematology and cancer. The company is headquartered in Breda, the Netherlands.

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