WallStSmart

Ascendis Pharma AS (ASND)vsBeiGene, Ltd. (ONC)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

BeiGene, Ltd. generates 563% more annual revenue ($5.74B vs $865.78M). ASND leads profitability with a 57.3% profit margin vs 8.9%. ASND trades at a lower P/E of 29.4x. ASND earns a higher WallStSmart Score of 55/100 (C).

ASND

Buy

55

out of 100

Grade: C

Growth: 8.0Profit: 7.0Value: 5.3Quality: 3.0
Piotroski: 3/9Altman Z: -2.66

ONC

Buy

54

out of 100

Grade: C-

Growth: 10.0Profit: 6.5Value: 5.7Quality: 7.0
Piotroski: 5/9Altman Z: 0.75
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for ASND.

ONCUndervalued (+81.0%)

Margin of Safety

+81.0%

Fair Value

$1847.00

Current Price

$322.08

$1524.92 discount

UndervaluedFair: $1847.00Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ASND3 strengths · Avg: 10.0/10
Return on EquityProfitability
103.7%10/10

Every $100 of equity generates 104 in profit

Profit MarginProfitability
57.3%10/10

Keeps 57 of every $100 in revenue as profit

Revenue GrowthGrowth
144.3%10/10

Revenue surging 144.3% year-over-year

ONC3 strengths · Avg: 9.7/10
Revenue GrowthGrowth
35.5%10/10

Revenue surging 35.5% year-over-year

EPS GrowthGrowth
16971.0%10/10

Earnings expanding 16971.0% YoY

Debt/EquityHealth
0.249/10

Conservative balance sheet, low leverage

Areas to Watch

ASND4 concerns · Avg: 3.5/10
P/E RatioValuation
29.4x4/10

Moderate valuation

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.843/10

Elevated debt levels

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

ONC2 concerns · Avg: 2.0/10
P/E RatioValuation
74.6x2/10

Premium valuation, high expectations priced in

Altman Z-ScoreHealth
0.752/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ASND

The strongest argument for ASND centers on Return on Equity, Profit Margin, Revenue Growth. Profitability is solid with margins at 57.3% and operating margin at 10.1%. Revenue growth of 144.3% demonstrates continued momentum.

Bull Case : ONC

The strongest argument for ONC centers on Revenue Growth, EPS Growth, Debt/Equity. Revenue growth of 35.5% demonstrates continued momentum.

Bear Case : ASND

The primary concerns for ASND are P/E Ratio, EPS Growth, Debt/Equity. Debt-to-equity of 1.84 is elevated, increasing financial risk.

Bear Case : ONC

The primary concerns for ONC are P/E Ratio, Altman Z-Score. A P/E of 74.6x leaves little room for execution misses.

Key Dynamics to Monitor

ASND profiles as a growth stock while ONC is a hypergrowth play — different risk/reward profiles.

ONC carries more volatility with a beta of 0.49 — expect wider price swings.

ASND is growing revenue faster at 144.3% — sustainability is the question.

ONC generates stronger free cash flow (161M), providing more financial flexibility.

Bottom Line

ASND scores higher overall (55/100 vs 54/100), backed by strong 57.3% margins and 144.3% revenue growth. ONC offers better value entry with a 81.0% margin of safety. Both earn "Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Ascendis Pharma AS

HEALTHCARE · BIOTECHNOLOGY · USA

Ascendis Pharma A / S, a biopharmaceutical company, develops therapies for unmet medical needs. The company is headquartered in Hellerup, Denmark.

BeiGene, Ltd.

HEALTHCARE · BIOTECHNOLOGY · USA

BeiGene, Ltd., an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company is headquartered in Camana Bay, the Cayman Islands.

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