WallStSmart

Ascendis Pharma AS (ASND)vsRegeneron Pharmaceuticals Inc (REGN)

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Smart Verdict

WallStSmart Research — data-driven comparison

Regeneron Pharmaceuticals Inc generates 1384% more annual revenue ($15.53B vs $1.05B). ASND leads profitability with a 70.9% profit margin vs 27.9%. REGN trades at a lower P/E of 19.6x. REGN earns a higher WallStSmart Score of 66/100 (B-).

ASND

Buy

61

out of 100

Grade: C+

Growth: 8.0Profit: 9.5Value: 5.3Quality: 5.5
Piotroski: 3/9Altman Z: -2.66

REGN

Strong Buy

66

out of 100

Grade: B-

Growth: 5.3Profit: 8.0Value: 7.3Quality: 8.5
Piotroski: 2/9Altman Z: 4.44
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

Intrinsic value data unavailable for ASND.

REGNUndervalued (+44.4%)

Margin of Safety

+44.4%

Fair Value

$1404.34

Current Price

$781.49

$622.85 discount

UndervaluedFair: $1404.34Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ASND4 strengths · Avg: 10.0/10
Return on EquityProfitability
52.6%10/10

Every $100 of equity generates 53 in profit

Profit MarginProfitability
70.9%10/10

Keeps 71 of every $100 in revenue as profit

Operating MarginProfitability
65.0%10/10

Strong operational efficiency at 65.0%

Revenue GrowthGrowth
114.7%10/10

Revenue surging 114.7% year-over-year

REGN6 strengths · Avg: 9.3/10
Operating MarginProfitability
33.1%10/10

Strong operational efficiency at 33.1%

Debt/EquityHealth
0.0610/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.4410/10

Safe zone — low bankruptcy risk

Market CapQuality
$80.46B9/10

Large-cap with strong market position

Profit MarginProfitability
27.9%9/10

Keeps 28 of every $100 in revenue as profit

Price/BookValuation
2.5x8/10

Reasonable price relative to book value

Areas to Watch

ASND4 concerns · Avg: 3.3/10
Price/BookValuation
10.4x4/10

Trading at 10.4x book value

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

Altman Z-ScoreHealth
-2.662/10

Distress zone — elevated risk

REGN2 concerns · Avg: 2.5/10
Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

EPS GrowthGrowth
-4.5%2/10

Earnings declined 4.5%

Comparative Analysis Report

WallStSmart Research

Bull Case : ASND

The strongest argument for ASND centers on Return on Equity, Profit Margin, Operating Margin. Profitability is solid with margins at 70.9% and operating margin at 65.0%. Revenue growth of 114.7% demonstrates continued momentum.

Bull Case : REGN

The strongest argument for REGN centers on Operating Margin, Debt/Equity, Altman Z-Score. Profitability is solid with margins at 27.9% and operating margin at 33.1%. Revenue growth of 16.7% demonstrates continued momentum.

Bear Case : ASND

The primary concerns for ASND are Price/Book, EPS Growth, Piotroski F-Score.

Bear Case : REGN

The primary concerns for REGN are Piotroski F-Score, EPS Growth.

Key Dynamics to Monitor

ASND carries more volatility with a beta of 0.48 — expect wider price swings.

ASND is growing revenue faster at 114.7% — sustainability is the question.

REGN generates stronger free cash flow (334M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

REGN scores higher overall (66/100 vs 61/100), backed by strong 27.9% margins and 16.7% revenue growth. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Ascendis Pharma AS

HEALTHCARE · BIOTECHNOLOGY · USA

Ascendis Pharma A / S, a biopharmaceutical company, develops therapies for unmet medical needs. The company is headquartered in Hellerup, Denmark.

Regeneron Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Regeneron Pharmaceuticals, Inc. is an American biotechnology company headquartered in Westchester County, New York. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the company then branched out into the study of both cytokine and tyrosine kinase receptors.

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