WallStSmart

Axsome Therapeutics Inc (AXSM)vsRoyalty Pharma Plc (RPRX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Royalty Pharma Plc generates 245% more annual revenue ($2.44B vs $708.24M). RPRX leads profitability with a 33.9% profit margin vs -26.6%. RPRX earns a higher WallStSmart Score of 65/100 (C+).

AXSM

Avoid

31

out of 100

Grade: F

Growth: 8.0Profit: 2.0Value: 6.7Quality: 3.5
Piotroski: 5/9Altman Z: -2.12

RPRX

Buy

65

out of 100

Grade: C+

Growth: 6.0Profit: 8.0Value: 4.0Quality: 5.0
Piotroski: 2/9Altman Z: 1.15
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AXSMUndervalued (+50.8%)

Margin of Safety

+50.8%

Fair Value

$378.56

Current Price

$232.32

$146.24 discount

UndervaluedFair: $378.56Overvalued
RPRXSignificantly Overvalued (-59.6%)

Margin of Safety

-59.6%

Fair Value

$34.38

Current Price

$55.02

$20.64 premium

UndervaluedFair: $34.38Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AXSM1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
57.4%10/10

Revenue surging 57.4% year-over-year

RPRX3 strengths · Avg: 9.3/10
Profit MarginProfitability
33.9%10/10

Keeps 34 of every $100 in revenue as profit

Operating MarginProfitability
100.3%10/10

Strong operational efficiency at 100.3%

EPS GrowthGrowth
23.2%8/10

Earnings expanding 23.2% YoY

Areas to Watch

AXSM4 concerns · Avg: 2.5/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Price/BookValuation
219.2x2/10

Trading at 219.2x book value

Return on EquityProfitability
-345.0%2/10

ROE of -345.0% — below average capital efficiency

Free Cash FlowQuality
$-20.82M2/10

Negative free cash flow — burning cash

RPRX4 concerns · Avg: 3.5/10
PEG RatioValuation
2.054/10

Expensive relative to growth rate

P/E RatioValuation
28.9x4/10

Moderate valuation

Debt/EquityHealth
1.303/10

Elevated debt levels

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : AXSM

The strongest argument for AXSM centers on Revenue Growth. Revenue growth of 57.4% demonstrates continued momentum.

Bull Case : RPRX

The strongest argument for RPRX centers on Profit Margin, Operating Margin, EPS Growth. Profitability is solid with margins at 33.9% and operating margin at 100.3%. Revenue growth of 11.0% demonstrates continued momentum.

Bear Case : AXSM

The primary concerns for AXSM are EPS Growth, Price/Book, Return on Equity. Debt-to-equity of 3.97 is elevated, increasing financial risk.

Bear Case : RPRX

The primary concerns for RPRX are PEG Ratio, P/E Ratio, Debt/Equity.

Key Dynamics to Monitor

AXSM profiles as a hypergrowth stock while RPRX is a mature play — different risk/reward profiles.

AXSM carries more volatility with a beta of 0.60 — expect wider price swings.

AXSM is growing revenue faster at 57.4% — sustainability is the question.

RPRX generates stronger free cash flow (761M), providing more financial flexibility.

Bottom Line

RPRX scores higher overall (65/100 vs 31/100), backed by strong 33.9% margins and 11.0% revenue growth. AXSM offers better value entry with a 50.8% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Axsome Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Axsome Therapeutics, Inc., a biopharmaceutical company, is dedicated to developing new therapies for central nervous system (CNS) disorders in the United States. The company is headquartered in New York, New York.

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Royalty Pharma Plc

HEALTHCARE · BIOTECHNOLOGY · USA

Royalty Pharma plc is a buyer of biopharmaceutical royalties and funder of innovations in the biopharmaceutical industry in the United States. The company is headquartered in New York, New York.

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