WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsRoyalty Pharma Plc (RPRX)

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Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 56% more annual revenue ($3.71B vs $2.38B). RPRX leads profitability with a 32.4% profit margin vs 8.4%. RPRX trades at a lower P/E of 25.8x. RPRX earns a higher WallStSmart Score of 61/100 (C+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

RPRX

Buy

61

out of 100

Grade: C+

Growth: 4.7Profit: 8.0Value: 7.3Quality: 5.0
Piotroski: 2/9Altman Z: 1.15
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1934.6%)

Margin of Safety

-1934.6%

Fair Value

$15.84

Current Price

$312.17

$296.33 premium

UndervaluedFair: $15.84Overvalued
RPRXSignificantly Overvalued (-17.3%)

Margin of Safety

-17.3%

Fair Value

$37.74

Current Price

$45.36

$7.62 premium

UndervaluedFair: $37.74Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

RPRX2 strengths · Avg: 10.0/10
Profit MarginProfitability
32.4%10/10

Keeps 32 of every $100 in revenue as profit

Operating MarginProfitability
57.7%10/10

Strong operational efficiency at 57.7%

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
136.9x2/10

Premium valuation, high expectations priced in

Price/BookValuation
52.4x2/10

Trading at 52.4x book value

RPRX4 concerns · Avg: 3.5/10
P/E RatioValuation
25.8x4/10

Moderate valuation

Revenue GrowthGrowth
4.8%4/10

4.8% revenue growth

Debt/EquityHealth
1.383/10

Elevated debt levels

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : RPRX

The strongest argument for RPRX centers on Profit Margin, Operating Margin. Profitability is solid with margins at 32.4% and operating margin at 57.7%. PEG of 1.39 suggests the stock is reasonably priced for its growth.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 136.9x leaves little room for execution misses.

Bear Case : RPRX

The primary concerns for RPRX are P/E Ratio, Revenue Growth, Debt/Equity.

Key Dynamics to Monitor

ALNY profiles as a hypergrowth stock while RPRX is a value play — different risk/reward profiles.

RPRX carries more volatility with a beta of 0.42 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

RPRX generates stronger free cash flow (827M), providing more financial flexibility.

Bottom Line

RPRX scores higher overall (61/100 vs 49/100), backed by strong 32.4% margins. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Royalty Pharma Plc

HEALTHCARE · BIOTECHNOLOGY · USA

Royalty Pharma plc is a buyer of biopharmaceutical royalties and funder of innovations in the biopharmaceutical industry in the United States. The company is headquartered in New York, New York.

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