WallStSmart

AstraZeneca PLC (AZN)vsCrinetics Pharmaceuticals Inc (CRNX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 334390% more annual revenue ($60.44B vs $18.07M). AZN leads profitability with a 17.2% profit margin vs 0.0%. AZN earns a higher WallStSmart Score of 64/100 (C+).

AZN

Buy

64

out of 100

Grade: C+

Growth: 6.0Profit: 8.5Value: 6.0Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

CRNX

Hold

37

out of 100

Grade: F

Growth: 7.3Profit: 2.5Value: 6.7Quality: 7.5
Piotroski: 2/9Altman Z: 1.93
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+8.2%)

Margin of Safety

+8.2%

Fair Value

$194.77

Current Price

$185.95

$8.82 discount

UndervaluedFair: $194.77Overvalued
CRNXUndervalued (+71.6%)

Margin of Safety

+71.6%

Fair Value

$167.58

Current Price

$32.92

$134.66 discount

UndervaluedFair: $167.58Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$282.69B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
21.9%9/10

Every $100 of equity generates 22 in profit

Operating MarginProfitability
27.9%8/10

Strong operational efficiency at 27.9%

Free Cash FlowQuality
$1.82B8/10

Generating 1.8B in free cash flow

CRNX3 strengths · Avg: 9.3/10
Revenue GrowthGrowth
2873.0%10/10

Revenue surging 2873.0% year-over-year

Debt/EquityHealth
0.0410/10

Conservative balance sheet, low leverage

Price/BookValuation
2.7x8/10

Reasonable price relative to book value

Areas to Watch

AZN2 concerns · Avg: 3.0/10
P/E RatioValuation
27.5x4/10

Moderate valuation

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

CRNX4 concerns · Avg: 3.5/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Altman Z-ScoreHealth
1.934/10

Grey zone — moderate risk

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.2% and operating margin at 27.9%. Revenue growth of 12.5% demonstrates continued momentum.

Bull Case : CRNX

The strongest argument for CRNX centers on Revenue Growth, Debt/Equity, Price/Book. Revenue growth of 2873.0% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are P/E Ratio, Altman Z-Score.

Bear Case : CRNX

The primary concerns for CRNX are EPS Growth, Altman Z-Score, Profit Margin.

Key Dynamics to Monitor

AZN profiles as a mature stock while CRNX is a hypergrowth play — different risk/reward profiles.

CRNX carries more volatility with a beta of 0.24 — expect wider price swings.

CRNX is growing revenue faster at 2873.0% — sustainability is the question.

AZN generates stronger free cash flow (1.8B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (64/100 vs 37/100), backed by strong 17.2% margins and 12.5% revenue growth. CRNX offers better value entry with a 71.6% margin of safety. Both earn "Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Crinetics Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of therapies for rare endocrine diseases and endocrine-related tumors. The company is headquartered in San Diego, California.

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