WallStSmart

AstraZeneca PLC (AZN)vsCrinetics Pharmaceuticals Inc (CRNX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

AstraZeneca PLC generates 145469% more annual revenue ($61.37B vs $42.16M). AZN leads profitability with a 17.0% profit margin vs 0.0%. AZN earns a higher WallStSmart Score of 60/100 (C+).

AZN

Buy

60

out of 100

Grade: C+

Growth: 5.3Profit: 8.0Value: 6.7Quality: 5.0
Piotroski: 6/9Altman Z: 1.48

CRNX

Avoid

32

out of 100

Grade: F

Growth: 7.3Profit: 2.5Value: 6.7Quality: 8.0
Piotroski: 2/9Altman Z: 2.08
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

AZNUndervalued (+18.4%)

Margin of Safety

+18.4%

Fair Value

$196.10

Current Price

$160.17

$35.93 discount

UndervaluedFair: $196.10Overvalued
CRNXUndervalued (+87.2%)

Margin of Safety

+87.2%

Fair Value

$370.52

Current Price

$84.95

$285.57 discount

UndervaluedFair: $370.52Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

AZN4 strengths · Avg: 8.8/10
Market CapQuality
$252.33B10/10

Mega-cap, among the largest globally

Return on EquityProfitability
20.8%9/10

Every $100 of equity generates 21 in profit

Operating MarginProfitability
23.5%8/10

Strong operational efficiency at 23.5%

Free Cash FlowQuality
$2.13B8/10

Generating 2.1B in free cash flow

CRNX2 strengths · Avg: 10.0/10
Revenue GrowthGrowth
2336.0%10/10

Revenue surging 2336.0% year-over-year

Debt/EquityHealth
0.0410/10

Conservative balance sheet, low leverage

Areas to Watch

AZN2 concerns · Avg: 3.0/10
EPS GrowthGrowth
2.5%4/10

2.5% earnings growth

Altman Z-ScoreHealth
1.482/10

Distress zone — elevated risk

CRNX4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Return on EquityProfitability
-38.8%2/10

ROE of -38.8% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : AZN

The strongest argument for AZN centers on Market Cap, Return on Equity, Operating Margin. Profitability is solid with margins at 17.0% and operating margin at 23.5%. PEG of 1.28 suggests the stock is reasonably priced for its growth.

Bull Case : CRNX

The strongest argument for CRNX centers on Revenue Growth, Debt/Equity. Revenue growth of 2336.0% demonstrates continued momentum.

Bear Case : AZN

The primary concerns for AZN are EPS Growth, Altman Z-Score.

Bear Case : CRNX

The primary concerns for CRNX are EPS Growth, Profit Margin, Piotroski F-Score.

Key Dynamics to Monitor

AZN profiles as a mature stock while CRNX is a hypergrowth play — different risk/reward profiles.

AZN carries more volatility with a beta of 0.20 — expect wider price swings.

CRNX is growing revenue faster at 2336.0% — sustainability is the question.

AZN generates stronger free cash flow (2.1B), providing more financial flexibility.

Bottom Line

AZN scores higher overall (60/100 vs 32/100), backed by strong 17.0% margins. CRNX offers better value entry with a 87.2% margin of safety. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

AstraZeneca PLC

HEALTHCARE · DRUG MANUFACTURERS - GENERAL · USA

AstraZeneca PLC discovers, develops, manufactures and markets prescription drugs in the areas of oncology, cardiovascular, renal and metabolism, respiratory, infections, neuroscience and gastroenterology worldwide. The company is headquartered in Cambridge, the United Kingdom.

Crinetics Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of therapies for rare endocrine diseases and endocrine-related tumors. The company is headquartered in San Diego, California.

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