WallStSmart

Ginkgo Bioworks Holdings (DNA)vsRoyalty Pharma Plc (RPRX)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Royalty Pharma Plc generates 1512% more annual revenue ($2.44B vs $151.40M). RPRX leads profitability with a 33.9% profit margin vs -201.0%. RPRX earns a higher WallStSmart Score of 65/100 (C+).

DNA

Avoid

29

out of 100

Grade: F

Growth: 2.7Profit: 2.0Value: 4.7Quality: 5.5
Piotroski: 2/9Altman Z: -7.56

RPRX

Buy

65

out of 100

Grade: C+

Growth: 6.0Profit: 8.0Value: 4.0Quality: 5.0
Piotroski: 2/9Altman Z: 1.15
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

DNAOvervalued (-7.5%)

Margin of Safety

-7.5%

Fair Value

$8.70

Current Price

$8.22

$0.48 premium

UndervaluedFair: $8.70Overvalued
RPRXSignificantly Overvalued (-53.4%)

Margin of Safety

-53.4%

Fair Value

$34.53

Current Price

$55.02

$20.49 premium

UndervaluedFair: $34.53Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

DNA1 strengths · Avg: 10.0/10
Price/BookValuation
1.1x10/10

Reasonable price relative to book value

RPRX3 strengths · Avg: 9.3/10
Profit MarginProfitability
33.9%10/10

Keeps 34 of every $100 in revenue as profit

Operating MarginProfitability
100.3%10/10

Strong operational efficiency at 100.3%

EPS GrowthGrowth
23.2%8/10

Earnings expanding 23.2% YoY

Areas to Watch

DNA4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$577.47M3/10

Smaller company, higher risk/reward

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Return on EquityProfitability
-68.7%2/10

ROE of -68.7% — below average capital efficiency

RPRX4 concerns · Avg: 3.5/10
PEG RatioValuation
2.054/10

Expensive relative to growth rate

P/E RatioValuation
28.9x4/10

Moderate valuation

Debt/EquityHealth
1.303/10

Elevated debt levels

Piotroski F-ScoreQuality
2/93/10

Weak financial health signals

Comparative Analysis Report

WallStSmart Research

Bull Case : DNA

The strongest argument for DNA centers on Price/Book.

Bull Case : RPRX

The strongest argument for RPRX centers on Profit Margin, Operating Margin, EPS Growth. Profitability is solid with margins at 33.9% and operating margin at 100.3%. Revenue growth of 11.0% demonstrates continued momentum.

Bear Case : DNA

The primary concerns for DNA are EPS Growth, Market Cap, Piotroski F-Score.

Bear Case : RPRX

The primary concerns for RPRX are PEG Ratio, P/E Ratio, Debt/Equity.

Key Dynamics to Monitor

DNA profiles as a turnaround stock while RPRX is a mature play — different risk/reward profiles.

DNA carries more volatility with a beta of 1.80 — expect wider price swings.

RPRX is growing revenue faster at 11.0% — sustainability is the question.

RPRX generates stronger free cash flow (761M), providing more financial flexibility.

Bottom Line

RPRX scores higher overall (65/100 vs 29/100), backed by strong 33.9% margins and 11.0% revenue growth. Both earn "Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Ginkgo Bioworks Holdings

HEALTHCARE · BIOTECHNOLOGY · USA

Ginkgo Bioworks Holdings (DNA) is a leader in synthetic biology, specializing in advanced genetic engineering to develop tailor-made bioengineered organisms for diverse applications, including pharmaceuticals, agriculture, and industrial biotech. Its cutting-edge platform enhances cellular design for efficient manufacturing processes, positioning the company to meet pressing global challenges such as climate change and food security. Ginkgo's unique capabilities and focus on sustainable biotechnology solutions not only address growing market demands for bio-based alternatives but also signify a compelling growth trajectory, underscoring its potential to drive transformative impact across multiple industries.

Royalty Pharma Plc

HEALTHCARE · BIOTECHNOLOGY · USA

Royalty Pharma plc is a buyer of biopharmaceutical royalties and funder of innovations in the biopharmaceutical industry in the United States. The company is headquartered in New York, New York.

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