WallStSmart

ACADIA Pharmaceuticals Inc (ACAD)vsAlnylam Pharmaceuticals Inc (ALNY)

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Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 247% more annual revenue ($3.71B vs $1.07B). ACAD leads profitability with a 36.5% profit margin vs 8.5%. ACAD trades at a lower P/E of 9.1x. ACAD earns a higher WallStSmart Score of 66/100 (B-).

ACAD

Strong Buy

66

out of 100

Grade: B-

Growth: 8.7Profit: 8.0Value: 7.3Quality: 6.0
Piotroski: 3/9

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ACADUndervalued (+79.1%)

Margin of Safety

+79.1%

Fair Value

$107.64

Current Price

$22.01

$85.63 discount

UndervaluedFair: $107.64Overvalued
ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ACAD4 strengths · Avg: 10.0/10
P/E RatioValuation
9.1x10/10

Attractively priced relative to earnings

Return on EquityProfitability
39.9%10/10

Every $100 of equity generates 40 in profit

Profit MarginProfitability
36.5%10/10

Keeps 37 of every $100 in revenue as profit

EPS GrowthGrowth
86.2%10/10

Earnings expanding 86.2% YoY

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

Areas to Watch

ACAD3 concerns · Avg: 2.3/10
Piotroski F-ScoreQuality
3/93/10

Weak financial health signals

PEG RatioValuation
50.862/10

Expensive relative to growth rate

Free Cash FlowQuality
$-52.74M2/10

Negative free cash flow — burning cash

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : ACAD

The strongest argument for ACAD centers on P/E Ratio, Return on Equity, Profit Margin. Profitability is solid with margins at 36.5% and operating margin at 6.1%.

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bear Case : ACAD

The primary concerns for ACAD are Piotroski F-Score, PEG Ratio, Free Cash Flow.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Key Dynamics to Monitor

ACAD profiles as a mature stock while ALNY is a hypergrowth play — different risk/reward profiles.

ACAD carries more volatility with a beta of 0.81 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Bottom Line

ACAD scores higher overall (66/100 vs 49/100), backed by strong 36.5% margins. Both earn "Strong Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

ACADIA Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of small molecule drugs that address unmet medical needs in central nervous system disorders. The company is headquartered in San Diego, California.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

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