WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsBeiGene, Ltd. (ONC)

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Smart Verdict

WallStSmart Research — data-driven comparison

BeiGene, Ltd. generates 28% more annual revenue ($6.13B vs $4.80B). ALNY leads profitability with a 16.1% profit margin vs 10.7%. ALNY appears more attractively valued with a PEG of 0.29. ALNY earns a higher WallStSmart Score of 68/100 (B-).

ALNY

Strong Buy

68

out of 100

Grade: B-

Growth: 8.0Profit: 8.5Value: 8.0Quality: 6.0
Piotroski: 4/9Altman Z: -0.02

ONC

Buy

64

out of 100

Grade: C+

Growth: 9.3Profit: 6.5Value: 6.7Quality: 7.0
Piotroski: 5/9Altman Z: 0.75
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+87.3%)

Margin of Safety

+87.3%

Fair Value

$2546.59

Current Price

$174.00

$2372.59 discount

UndervaluedFair: $2546.59Overvalued
ONCUndervalued (+79.6%)

Margin of Safety

+79.6%

Fair Value

$1720.81

Current Price

$371.56

$1349.25 discount

UndervaluedFair: $1720.81Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY3 strengths · Avg: 10.0/10
PEG RatioValuation
0.2910/10

Growing faster than its price suggests

Return on EquityProfitability
59.7%10/10

Every $100 of equity generates 60 in profit

Revenue GrowthGrowth
66.9%10/10

Revenue surging 66.9% year-over-year

ONC4 strengths · Avg: 8.8/10
EPS GrowthGrowth
166.7%10/10

Earnings expanding 166.7% YoY

Debt/EquityHealth
0.229/10

Conservative balance sheet, low leverage

PEG RatioValuation
0.778/10

Growing faster than its price suggests

Revenue GrowthGrowth
29.6%8/10

Revenue surging 29.6% year-over-year

Areas to Watch

ALNY4 concerns · Avg: 3.5/10
P/E RatioValuation
39.2x4/10

Premium valuation, high expectations priced in

Price/BookValuation
17.2x4/10

Trading at 17.2x book value

EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Altman Z-ScoreHealth
-0.022/10

Distress zone — elevated risk

ONC3 concerns · Avg: 2.7/10
Price/BookValuation
8.1x4/10

Trading at 8.1x book value

P/E RatioValuation
67.5x2/10

Premium valuation, high expectations priced in

Altman Z-ScoreHealth
0.752/10

Distress zone — elevated risk

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on PEG Ratio, Return on Equity, Revenue Growth. Profitability is solid with margins at 16.1% and operating margin at 17.9%. Revenue growth of 66.9% demonstrates continued momentum.

Bull Case : ONC

The strongest argument for ONC centers on EPS Growth, Debt/Equity, PEG Ratio. Revenue growth of 29.6% demonstrates continued momentum. PEG of 0.77 suggests the stock is reasonably priced for its growth.

Bear Case : ALNY

The primary concerns for ALNY are P/E Ratio, Price/Book, EPS Growth.

Bear Case : ONC

The primary concerns for ONC are Price/Book, P/E Ratio, Altman Z-Score. A P/E of 67.5x leaves little room for execution misses.

Key Dynamics to Monitor

ONC carries more volatility with a beta of 0.61 — expect wider price swings.

ALNY is growing revenue faster at 66.9% — sustainability is the question.

ONC generates stronger free cash flow (596M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (68/100 vs 64/100), backed by strong 16.1% margins and 66.9% revenue growth. ONC offers better value entry with a 79.6% margin of safety. Both earn "Strong Buy" and "Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

BeiGene, Ltd.

HEALTHCARE · BIOTECHNOLOGY · USA

BeiGene, Ltd., an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company is headquartered in Camana Bay, the Cayman Islands.

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