WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsAnaptysBio Inc (ANAB)

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Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 1483% more annual revenue ($3.71B vs $234.60M). ALNY leads profitability with a 8.5% profit margin vs -5.6%. ALNY earns a higher WallStSmart Score of 49/100 (D+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

ANAB

Hold

38

out of 100

Grade: F

Growth: 8.0Profit: 5.0Value: 5.0Quality: 7.0
Piotroski: 4/9Altman Z: -0.32
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued

Intrinsic value data unavailable for ANAB.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

ANAB3 strengths · Avg: 10.0/10
Operating MarginProfitability
61.8%10/10

Strong operational efficiency at 61.8%

Revenue GrowthGrowth
151.1%10/10

Revenue surging 151.1% year-over-year

Debt/EquityHealth
-11.7810/10

Conservative balance sheet, low leverage

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

ANAB4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$1.88B3/10

Smaller company, higher risk/reward

Price/BookValuation
49.2x2/10

Trading at 49.2x book value

Return on EquityProfitability
-24.5%2/10

ROE of -24.5% — below average capital efficiency

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : ANAB

The strongest argument for ANAB centers on Operating Margin, Revenue Growth, Debt/Equity. Revenue growth of 151.1% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : ANAB

The primary concerns for ANAB are EPS Growth, Market Cap, Price/Book.

Key Dynamics to Monitor

ANAB carries more volatility with a beta of 0.41 — expect wider price swings.

ANAB is growing revenue faster at 151.1% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (49/100 vs 38/100) and 84.9% revenue growth. Both earn "Hold" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

AnaptysBio Inc

HEALTHCARE · BIOTECHNOLOGY · USA

AnaptysBio, Inc., a clinical-stage biotechnology company, is dedicated to developing therapeutic product candidates for inflammation and immuno-oncology indications. The company is headquartered in San Diego, California.

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