WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsExelixis Inc (EXEL)

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Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 80% more annual revenue ($4.29B vs $2.38B). EXEL leads profitability with a 35.1% profit margin vs 12.6%. ALNY appears more attractively valued with a PEG of 0.48. EXEL earns a higher WallStSmart Score of 72/100 (B).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 7.3Quality: 5.5
Piotroski: 4/9Altman Z: -0.07

EXEL

Strong Buy

72

out of 100

Grade: B

Growth: 8.0Profit: 10.0Value: 7.3Quality: 9.0
Piotroski: 4/9Altman Z: 4.15
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.4%)

Margin of Safety

+86.4%

Fair Value

$2372.19

Current Price

$303.05

$2069.14 discount

UndervaluedFair: $2372.19Overvalued
EXELUndervalued (+67.2%)

Margin of Safety

+67.2%

Fair Value

$161.90

Current Price

$52.49

$109.41 discount

UndervaluedFair: $161.90Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.5/10
PEG RatioValuation
0.4810/10

Growing faster than its price suggests

Return on EquityProfitability
53.7%10/10

Every $100 of equity generates 54 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

EXEL6 strengths · Avg: 9.7/10
Return on EquityProfitability
43.0%10/10

Every $100 of equity generates 43 in profit

Profit MarginProfitability
35.1%10/10

Keeps 35 of every $100 in revenue as profit

Operating MarginProfitability
41.1%10/10

Strong operational efficiency at 41.1%

Debt/EquityHealth
0.0910/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
4.1510/10

Safe zone — low bankruptcy risk

P/E RatioValuation
17.6x8/10

Attractively priced relative to earnings

Areas to Watch

ALNY4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.183/10

Elevated debt levels

P/E RatioValuation
70.9x2/10

Premium valuation, high expectations priced in

Price/BookValuation
37.6x2/10

Trading at 37.6x book value

EXEL1 concerns · Avg: 4.0/10
PEG RatioValuation
2.274/10

Expensive relative to growth rate

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on PEG Ratio, Return on Equity, Revenue Growth. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.48 suggests the stock is reasonably priced for its growth.

Bull Case : EXEL

The strongest argument for EXEL centers on Return on Equity, Profit Margin, Operating Margin. Profitability is solid with margins at 35.1% and operating margin at 41.1%.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, Debt/Equity, P/E Ratio. A P/E of 70.9x leaves little room for execution misses.

Bear Case : EXEL

The primary concerns for EXEL are PEG Ratio.

Key Dynamics to Monitor

ALNY profiles as a growth stock while EXEL is a mature play — different risk/reward profiles.

EXEL carries more volatility with a beta of 0.43 — expect wider price swings.

ALNY is growing revenue faster at 96.4% — sustainability is the question.

EXEL generates stronger free cash flow (250M), providing more financial flexibility.

Bottom Line

EXEL scores higher overall (72/100 vs 65/100), backed by strong 35.1% margins. ALNY offers better value entry with a 86.4% margin of safety. Both earn "Strong Buy" and "Strong Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Exelixis Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Exelixis, Inc., an oncology-focused biotechnology company, is focused on the discovery, development, and commercialization of new drugs to treat cancers in the United States. The company is headquartered in Alameda, California.

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