WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsHalozyme Therapeutics Inc (HALO)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 166% more annual revenue ($3.71B vs $1.40B). HALO leads profitability with a 22.7% profit margin vs 8.5%. HALO trades at a lower P/E of 24.2x. HALO earns a higher WallStSmart Score of 70/100 (B).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

HALO

Strong Buy

70

out of 100

Grade: B

Growth: 10.0Profit: 8.0Value: 8.3Quality: 6.3
Piotroski: 4/9Altman Z: 2.91
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued
HALOUndervalued (+33.6%)

Margin of Safety

+33.6%

Fair Value

$119.81

Current Price

$63.24

$56.57 discount

UndervaluedFair: $119.81Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

HALO4 strengths · Avg: 9.3/10
Operating MarginProfitability
56.3%10/10

Strong operational efficiency at 56.3%

Revenue GrowthGrowth
51.6%10/10

Revenue surging 51.6% year-over-year

Profit MarginProfitability
22.7%9/10

Keeps 23 of every $100 in revenue as profit

EPS GrowthGrowth
36.2%8/10

Earnings expanding 36.2% YoY

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

HALO2 concerns · Avg: 2.5/10
Return on EquityProfitability
1.5%3/10

ROE of 1.5% — below average capital efficiency

Price/BookValuation
154.2x2/10

Trading at 154.2x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : HALO

The strongest argument for HALO centers on Operating Margin, Revenue Growth, Profit Margin. Profitability is solid with margins at 22.7% and operating margin at 56.3%. Revenue growth of 51.6% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : HALO

The primary concerns for HALO are Return on Equity, Price/Book.

Key Dynamics to Monitor

ALNY profiles as a hypergrowth stock while HALO is a growth play — different risk/reward profiles.

HALO carries more volatility with a beta of 1.02 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

HALO generates stronger free cash flow (218M), providing more financial flexibility.

Bottom Line

HALO scores higher overall (70/100 vs 49/100), backed by strong 22.7% margins and 51.6% revenue growth. Both earn "Strong Buy" and "Hold" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Halozyme Therapeutics Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Halozyme Therapeutics, Inc. is a biopharmaceutical technology platform company in the United States, Switzerland, Ireland, Belgium, Japan, and internationally. The company is headquartered in San Diego, California.

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