WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsIdeaya Biosciences Inc (IDYA)

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Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 1598% more annual revenue ($3.71B vs $218.71M). ALNY leads profitability with a 8.5% profit margin vs -52.0%. ALNY earns a higher WallStSmart Score of 49/100 (D+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

IDYA

Avoid

35

out of 100

Grade: F

Growth: 8.0Profit: 2.0Value: 5.0Quality: 9.0
Piotroski: 4/9Altman Z: 6.56
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued

Intrinsic value data unavailable for IDYA.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

IDYA4 strengths · Avg: 9.5/10
Revenue GrowthGrowth
55.4%10/10

Revenue surging 55.4% year-over-year

Debt/EquityHealth
0.0510/10

Conservative balance sheet, low leverage

Altman Z-ScoreHealth
6.5610/10

Safe zone — low bankruptcy risk

Price/BookValuation
2.7x8/10

Reasonable price relative to book value

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

IDYA4 concerns · Avg: 2.3/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Return on EquityProfitability
-10.9%2/10

ROE of -10.9% — below average capital efficiency

Free Cash FlowQuality
$-90.83M2/10

Negative free cash flow — burning cash

Profit MarginProfitability
-52.0%1/10

Currently unprofitable

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : IDYA

The strongest argument for IDYA centers on Revenue Growth, Debt/Equity, Altman Z-Score. Revenue growth of 55.4% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : IDYA

The primary concerns for IDYA are EPS Growth, Return on Equity, Free Cash Flow.

Key Dynamics to Monitor

ALNY carries more volatility with a beta of 0.38 — expect wider price swings.

ALNY is growing revenue faster at 84.9% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (49/100 vs 35/100) and 84.9% revenue growth. Both earn "Hold" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Ideaya Biosciences Inc

HEALTHCARE · BIOTECHNOLOGY · USA

IDEAYA Biosciences, Inc., a synthetic precision medicine oncology company focused on lethality, is focused on the discovery and development of targeted therapies for selected patient populations using molecular diagnostics. The company is headquartered in South San Francisco, California.

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