WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsLigand Pharmaceuticals Incorporated (LGND)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 1499% more annual revenue ($4.29B vs $268.09M). LGND leads profitability with a 46.4% profit margin vs 12.6%. ALNY appears more attractively valued with a PEG of 0.59. LGND earns a higher WallStSmart Score of 71/100 (B).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 6.7Quality: 5.0

LGND

Strong Buy

71

out of 100

Grade: B

Growth: 9.3Profit: 7.5Value: 6.0Quality: 8.5
Piotroski: 4/9Altman Z: 6.43
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.7%)

Margin of Safety

+86.7%

Fair Value

$2420.83

Current Price

$303.00

$2117.83 discount

UndervaluedFair: $2420.83Overvalued
LGNDUndervalued (+31.7%)

Margin of Safety

+31.7%

Fair Value

$272.20

Current Price

$232.55

$39.65 discount

UndervaluedFair: $272.20Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.0/10
Return on EquityProfitability
90.4%10/10

Every $100 of equity generates 90 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

PEG RatioValuation
0.598/10

Growing faster than its price suggests

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

LGND5 strengths · Avg: 10.0/10
Profit MarginProfitability
46.4%10/10

Keeps 46 of every $100 in revenue as profit

Operating MarginProfitability
33.6%10/10

Strong operational efficiency at 33.6%

Revenue GrowthGrowth
39.4%10/10

Revenue surging 39.4% year-over-year

EPS GrowthGrowth
103.2%10/10

Earnings expanding 103.2% YoY

Altman Z-ScoreHealth
6.4310/10

Safe zone — low bankruptcy risk

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
74.6x2/10

Premium valuation, high expectations priced in

Price/BookValuation
50.8x2/10

Trading at 50.8x book value

LGND2 concerns · Avg: 4.0/10
PEG RatioValuation
1.534/10

Expensive relative to growth rate

P/E RatioValuation
37.0x4/10

Premium valuation, high expectations priced in

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth, PEG Ratio. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.59 suggests the stock is reasonably priced for its growth.

Bull Case : LGND

The strongest argument for LGND centers on Profit Margin, Operating Margin, Revenue Growth. Profitability is solid with margins at 46.4% and operating margin at 33.6%. Revenue growth of 39.4% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 74.6x leaves little room for execution misses.

Bear Case : LGND

The primary concerns for LGND are PEG Ratio, P/E Ratio.

Key Dynamics to Monitor

LGND carries more volatility with a beta of 1.00 — expect wider price swings.

ALNY is growing revenue faster at 96.4% — sustainability is the question.

ALNY generates stronger free cash flow (49M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

LGND scores higher overall (71/100 vs 65/100), backed by strong 46.4% margins and 39.4% revenue growth. ALNY offers better value entry with a 86.7% margin of safety. Both earn "Strong Buy" and "Strong Buy" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Ligand Pharmaceuticals Incorporated

HEALTHCARE · BIOTECHNOLOGY · USA

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, focuses on developing or acquiring technologies that help pharmaceutical companies discover and develop drugs globally. The company is headquartered in San Diego, California.

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