WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsMesoblast Ltd (MESO)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 6457% more annual revenue ($4.29B vs $65.38M). ALNY leads profitability with a 12.6% profit margin vs -144.3%. ALNY earns a higher WallStSmart Score of 65/100 (B-).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 7.3Quality: 5.5
Piotroski: 4/9Altman Z: -0.02

MESO

Avoid

25

out of 100

Grade: F

Growth: 7.3Profit: 2.0Value: 6.7Quality: 6.5
Piotroski: 6/9Altman Z: -0.05
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.4%)

Margin of Safety

+86.4%

Fair Value

$2363.38

Current Price

$286.41

$2076.97 discount

UndervaluedFair: $2363.38Overvalued
MESOUndervalued (+44.1%)

Margin of Safety

+44.1%

Fair Value

$32.74

Current Price

$15.50

$17.24 discount

UndervaluedFair: $32.74Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.5/10
PEG RatioValuation
0.4810/10

Growing faster than its price suggests

Return on EquityProfitability
53.7%10/10

Every $100 of equity generates 54 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

MESO2 strengths · Avg: 9.5/10
Revenue GrowthGrowth
1527.0%10/10

Revenue surging 1527.0% year-over-year

Debt/EquityHealth
0.249/10

Conservative balance sheet, low leverage

Areas to Watch

ALNY4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Debt/EquityHealth
1.183/10

Elevated debt levels

P/E RatioValuation
70.9x2/10

Premium valuation, high expectations priced in

Price/BookValuation
35.5x2/10

Trading at 35.5x book value

MESO4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$1.80B3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-18.2%2/10

ROE of -18.2% — below average capital efficiency

Free Cash FlowQuality
$-4.46M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on PEG Ratio, Return on Equity, Revenue Growth. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.48 suggests the stock is reasonably priced for its growth.

Bull Case : MESO

The strongest argument for MESO centers on Revenue Growth, Debt/Equity. Revenue growth of 1527.0% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, Debt/Equity, P/E Ratio. A P/E of 70.9x leaves little room for execution misses.

Bear Case : MESO

The primary concerns for MESO are EPS Growth, Market Cap, Return on Equity.

Key Dynamics to Monitor

ALNY profiles as a growth stock while MESO is a hypergrowth play — different risk/reward profiles.

MESO carries more volatility with a beta of 0.79 — expect wider price swings.

MESO is growing revenue faster at 1527.0% — sustainability is the question.

ALNY generates stronger free cash flow (49M), providing more financial flexibility.

Bottom Line

ALNY scores higher overall (65/100 vs 25/100) and 96.4% revenue growth. MESO offers better value entry with a 44.1% margin of safety. Both earn "Strong Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Mesoblast Ltd

HEALTHCARE · BIOTECHNOLOGY · USA

Mesoblast Limited, a biopharmaceutical company, develops and markets allogeneic cellular drugs. The company is headquartered in Melbourne, Australia.

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