WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsMesoblast Ltd (MESO)

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Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 21495% more annual revenue ($3.71B vs $17.20M). ALNY leads profitability with a 8.5% profit margin vs 0.0%. ALNY earns a higher WallStSmart Score of 49/100 (D+).

ALNY

Hold

49

out of 100

Grade: D+

Growth: 8.0Profit: 7.0Value: 3.0Quality: 5.0

MESO

Avoid

27

out of 100

Grade: F

Growth: 7.3Profit: 2.5Value: 5.0Quality: 5.0
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYSignificantly Overvalued (-1925.6%)

Margin of Safety

-1925.6%

Fair Value

$15.91

Current Price

$328.70

$312.79 premium

UndervaluedFair: $15.91Overvalued

Intrinsic value data unavailable for MESO.

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY2 strengths · Avg: 10.0/10
Return on EquityProfitability
73.3%10/10

Every $100 of equity generates 73 in profit

Revenue GrowthGrowth
84.9%10/10

Revenue surging 84.9% year-over-year

MESO1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
458.6%10/10

Revenue surging 458.6% year-over-year

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
131.7x2/10

Premium valuation, high expectations priced in

Price/BookValuation
55.2x2/10

Trading at 55.2x book value

MESO4 concerns · Avg: 3.0/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$1.94B3/10

Smaller company, higher risk/reward

Profit MarginProfitability
0.0%3/10

0.0% margin — thin

Price/BookValuation
33.3x2/10

Trading at 33.3x book value

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth. Revenue growth of 84.9% demonstrates continued momentum.

Bull Case : MESO

The strongest argument for MESO centers on Revenue Growth. Revenue growth of 458.6% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 131.7x leaves little room for execution misses.

Bear Case : MESO

The primary concerns for MESO are EPS Growth, Market Cap, Profit Margin.

Key Dynamics to Monitor

MESO carries more volatility with a beta of 0.76 — expect wider price swings.

MESO is growing revenue faster at 458.6% — sustainability is the question.

ALNY generates stronger free cash flow (140M), providing more financial flexibility.

Monitor BIOTECHNOLOGY industry trends, competitive dynamics, and regulatory changes.

Bottom Line

ALNY scores higher overall (49/100 vs 27/100) and 84.9% revenue growth. Both earn "Hold" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Mesoblast Ltd

HEALTHCARE · BIOTECHNOLOGY · USA

Mesoblast Limited, a biopharmaceutical company, develops and markets allogeneic cellular drugs. The company is headquartered in Melbourne, Australia.

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