WallStSmart

Alnylam Pharmaceuticals Inc (ALNY)vsMesoblast Ltd (MESO)

VS

Smart Verdict

WallStSmart Research — data-driven comparison

Alnylam Pharmaceuticals Inc generates 6457% more annual revenue ($4.29B vs $65.38M). ALNY leads profitability with a 12.6% profit margin vs -144.3%. ALNY earns a higher WallStSmart Score of 65/100 (B-).

ALNY

Strong Buy

65

out of 100

Grade: B-

Growth: 8.0Profit: 8.0Value: 6.7Quality: 5.0

MESO

Avoid

25

out of 100

Grade: F

Growth: 7.3Profit: 2.0Value: 6.7Quality: 5.0
IV

Intrinsic Value Comparison

Multi-model valuation · Graham Formula

ALNYUndervalued (+86.6%)

Margin of Safety

+86.6%

Fair Value

$2410.60

Current Price

$295.05

$2115.55 discount

UndervaluedFair: $2410.60Overvalued
MESOUndervalued (+45.7%)

Margin of Safety

+45.7%

Fair Value

$33.69

Current Price

$14.74

$18.95 discount

UndervaluedFair: $33.69Overvalued

Key Strengths & Concerns

Side-by-side fundamental analysis

Key Strengths

ALNY4 strengths · Avg: 9.0/10
Return on EquityProfitability
90.4%10/10

Every $100 of equity generates 90 in profit

Revenue GrowthGrowth
96.4%10/10

Revenue surging 96.4% year-over-year

PEG RatioValuation
0.518/10

Growing faster than its price suggests

Operating MarginProfitability
23.0%8/10

Strong operational efficiency at 23.0%

MESO1 strengths · Avg: 10.0/10
Revenue GrowthGrowth
1527.0%10/10

Revenue surging 1527.0% year-over-year

Areas to Watch

ALNY3 concerns · Avg: 2.7/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

P/E RatioValuation
74.2x2/10

Premium valuation, high expectations priced in

Price/BookValuation
36.6x2/10

Trading at 36.6x book value

MESO4 concerns · Avg: 2.8/10
EPS GrowthGrowth
0.0%4/10

0.0% earnings growth

Market CapQuality
$1.91B3/10

Smaller company, higher risk/reward

Return on EquityProfitability
-18.2%2/10

ROE of -18.2% — below average capital efficiency

Free Cash FlowQuality
$-4.46M2/10

Negative free cash flow — burning cash

Comparative Analysis Report

WallStSmart Research

Bull Case : ALNY

The strongest argument for ALNY centers on Return on Equity, Revenue Growth, PEG Ratio. Revenue growth of 96.4% demonstrates continued momentum. PEG of 0.51 suggests the stock is reasonably priced for its growth.

Bull Case : MESO

The strongest argument for MESO centers on Revenue Growth. Revenue growth of 1527.0% demonstrates continued momentum.

Bear Case : ALNY

The primary concerns for ALNY are EPS Growth, P/E Ratio, Price/Book. A P/E of 74.2x leaves little room for execution misses.

Bear Case : MESO

The primary concerns for MESO are EPS Growth, Market Cap, Return on Equity.

Key Dynamics to Monitor

ALNY profiles as a growth stock while MESO is a hypergrowth play — different risk/reward profiles.

MESO carries more volatility with a beta of 0.79 — expect wider price swings.

MESO is growing revenue faster at 1527.0% — sustainability is the question.

ALNY generates stronger free cash flow (49M), providing more financial flexibility.

Bottom Line

ALNY scores higher overall (65/100 vs 25/100) and 96.4% revenue growth. MESO offers better value entry with a 45.7% margin of safety. Both earn "Strong Buy" and "Avoid" ratings respectively — the choice depends on your investment horizon and risk tolerance.

This analysis is generated from publicly available financial data. Not financial advice.

Alnylam Pharmaceuticals Inc

HEALTHCARE · BIOTECHNOLOGY · USA

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing and commercializing RNA interference (RNAi) therapies. The company is headquartered in Cambridge, Massachusetts.

Mesoblast Ltd

HEALTHCARE · BIOTECHNOLOGY · USA

Mesoblast Limited, a biopharmaceutical company, develops and markets allogeneic cellular drugs. The company is headquartered in Melbourne, Australia.

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